Complex formation reacations of (N.N'-dimethylethylenediamine) palladium(II) with various biologically relevant ligands

摘要

cis-Dichloro-(N.N'-dimethylethylenediamine)palladium(II) [pd(Me_2en)Cl_2] was synthesized and characterized. StoichiorIand stability constants of the complexes formed between [Pd(Me_2en)(H_2O)_]~(2+) with various biologically relevant ligands investigated. The ligands used are dicarboxylic acids, amino acids, peptides and DNA unit constituents, The results showed formation of I: I complexes with amino acids and dicarboxylic acids. Peptides forms both 1:1 complexes and the corresporu deprotonated amide species. DNA constituents form both 1:1 and 1:2 complexes. The concentration distribution of the compl, in solution was evaluated. [pd(Me_2en)Cl_2] and [Pd(Me_2en)(CBDCA)] were isolated and characterized by elemental analysis;FTIR,~1H NMR, mass spectra and thermal analysis (TGA).