DINUCLEAR NICKEL(II) COMPLEXES OF 2-HYDROXYACETOPHENONE N-4-SUBSTITUTED THIOSEMICARBAZONES

摘要

Dinuclear nickel(II) complexes with seven different 2-hydroxyacetophenone N-4-substituted thiosemicarbazones have been prepared and characterized. IR, electronic, H-1 and C-13 NMR spectra of the thiosemicarbazones and their complexes have been obtained. Both the thiosemicarbazones and their nickel(II) complexes have considerable growth inhibitory activity against Paecilomyces variotii, but none against Aspergillus niger. Generally, the thiosemicarbazones are more active than their nickel complexes, but the 2-hydroxyacetophenone N-4-dimethylthiosemicarbazone, H(2)Ap4DM, is less active than [Ni(Ap4DM)](2). The crystal structure of [Ni(Ap4DM)](2) is included in this study. [References: 28]