Syntheses,structures,electric conduction,electrochemical properties and antimicrobial activity of azomethine monomer and oligomer based on 4-hydroxybenzaldehyde and 2-aminopyridine

摘要

The effects of temperature (50-80 °C),reaction time (up to 15 h) as well as type and concentration of oxidizing agent (NaOCl,air O2,H2O2) on the course of oxidative polymerization of 4-[(pyridin-2-yl-imino)methyl]phenol (4-PIMP) in aqueous alkaline medium,and on the yield of the oligomers formed (O-4-PIMP) were investigated.The optimal conditions of the process have been found.Reaction products were characterized using the following methods:~1H NMR,~(13)C NMR,FT-IR,UV-VIS,gel permeation chromatography and thermal analyses TG-DTA.Mn values of 0-4-PIMP are in the range 1250-4450.The oligomer shows better thermal stability than the monomer.On the basis of voltammetric measurements' results the electrochemical properties of 4-PIMP and 0-4-PIMP were characterized in detail,including an effect of iodine doping of O-4-PIMP on the electric conduction.The comparison of antibacterial activity of 4-PIMP and O-4-PIMP against 8 bacterial strains has been done.