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首页> 外文期刊>Journal of Clinical Microbiology >Pulsed-Field Gel Electrophoresis Analysis of More than One Clinical Isolate of Campylobacter spp. from Each of 49 Patients in New Zealand
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Pulsed-Field Gel Electrophoresis Analysis of More than One Clinical Isolate of Campylobacter spp. from Each of 49 Patients in New Zealand

机译:弯曲杆菌属的一种以上临床分离株的脉冲场凝胶电泳分析。来自新西兰的49位患者中的每位

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摘要

Pulsed-field gel electrophoresis (PFGE) analysis demonstrated that while 76% of patients had only one genotype of campylobacter, 10% carried two different but related genotypes (Dice coefficients > 0.78), and 14% carried at least two unrelated genotypes (Dice coefficients < 0.65). This supports the clustering of Campylobacter isolates with similar PFGE patterns, highlights the need to analyze multiple isolates from both sources and patients, and confirms that caution should be exercised before epidemiological links between patients or sources are dismissed.
机译:脉冲场凝胶电泳(PFGE)分析表明,虽然76%的患者只有一种弯曲菌基因型,但10%的患者携带两种不同但相关的基因型(骰子系数> 0.78),而14%的患者至少携带两种不相关的基因型(骰子系数) <0.65)。这支持了具有相似PFGE模式的弯曲杆菌分离株的聚类,强调需要分析来自来源和患者的多种分离株,并确认在消除患者或来源之间的流行病学联系之前应谨慎行事。

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