Cross-reactions between Neisseria meningitidis group H and Escherichia coli K2 and K62 polysaccharides.

摘要

Neisseria meningitidis group H polysaccharide was found to cross-react in immunoprecipitation with cultures, culture supernatants, and purified polysaccharides from Escherichia coli O86:K62 and O6:K2 but not with those fractions from E. coli O6:K-. Antibodies to N. meningitidis group H polysaccharide could be absorbed completely with E. coli K62 and partly with E. coli K2 bacteria but not with E. coli K- bacteria. N. meningitidis H and E. coli K2 and K62 polysaccharides share the structure -phosphate----galactose (Gal)p----glycerol (Gro)-.