Monte Carlo-based rigid body modelling of large protein complexes against small angle scattering data

摘要

We present a modular, collaborative, open-source architecture for rigid body modelling based upon small angle scattering data, named sas-rigid. It is designed to provide a fast and extensible scripting interface using the easy-to-learn Python programming language. Features include rigid body modelling to result in static structures and three-dimensional probability densities using two different algorithms.