Color yes, toxicity no : Systematic approaches to meeting this challenge

摘要

This paper provides an overview of studies conducted at the North Carolina State University College of Textiles since the inception of the dye chemistry program in 1984. Design of new textile dyes to replace existing dyes and dye intermediates were studied with the goal of minimizing human health and environmental risks. Initially, correlations between chemical structures and environmental toxicity were established and the resulting information used in design studies. These studies resulted in nonmutagenic replacements for genotoxic aromatic amines used in azo dye development and metal complexed dyes based on benign alternatives to priority pollutants. Key technical properties of newly developed dyes and summaries of certain toxicological test methods and regulatory policies used to ensure dye application safety are presented.