首页> 美国卫生研究院文献>Frontiers in Nutrition >Early Dietary Patterns and Microbiota Development: Still a Way to Go from Descriptive Interactions to Health-Relevant Solutions
【2h】

Early Dietary Patterns and Microbiota Development: Still a Way to Go from Descriptive Interactions to Health-Relevant Solutions

机译:早期饮食模式和微生物群发育:从描述性相互作用到健康相关解决方案的一种途径

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。
获取外文期刊封面目录资料

摘要

Early nutrition and growth in the initial years of life are important determinants of later body weight and metabolic health in humans, and the current epidemic of obesity involving children requires a better understanding of causal and protective mechanisms and components in infant foods. This review focuses on recent evidence implicating feeding modes (e.g., breast milk and formula milk) and dietary transitions toward complementary foods in the progression of microbiota maturation in children. The literature exploring body weight outcomes of microbiota changes induced by diet in early life is limited. Representative studies addressing the use of probiotics in pregnant women and infants are also examined. Methodological and geo-cultural variations make it difficult to avoid (apparently) controversial findings. Most studies indicate differences in the microbiota of formula versus breastfed infants, but some do not. Duration of breastfeeding delays the maturation of the microbiota toward an adult-like profile. However, the effect size of the early feeding pattern on microbial function was found to be very small, and absent after the third year of life. There are several interesting mediators whereby milk composition can affect infants’ microbiota and their optimization is a desirable strategy for prevention. But prevention of what? Although there are few correlative evaluations relating microbiota and body weight in early life, studies demonstrating a cause–effect relationship between diet-induced changes in early microbiota development and subsequent metabolic health outcomes in humans are still missing.
机译:生命初期的早期营养和生长是决定人类后来体重和新陈代谢健康的重要决定因素,当前涉及儿童的肥胖病流行需要对婴儿食品的因果关系,保护机制和成分有更好的了解。这篇综述着重于最近的证据,暗示了儿童微生物群成熟过程中的喂养方式(例如母乳和配方乳)和饮食向辅食的过渡。在生命早期,饮食引起微生物群变化的体重结果研究文献有限。还研究了针对孕妇和婴儿使用益生菌的代表性研究。由于方法和地理文化的差异,很难避免(显然)有争议的发现。大多数研究表明,配方奶粉与母乳喂养婴儿的微生物区系存在差异,但有些则没有。母乳喂养的时间延迟了微生物群向成人状轮廓的成熟。但是,发现早期喂养方式对微生物功能的影响很小,并且在生命的第三年之后就没有了。有几种有趣的介体,乳成分可以影响婴儿的微生物群,优化它们的配方是预防的理想策略。但是预防什么呢?尽管很少有关于早期生命中微生物群和体重的相关评估,但仍缺乏表明饮食引起的早期微生物群发育变化与人类后续代谢健康结果之间因果关系的研究。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号