目的 比较不同ABCD2评分短暂性脑缺血发作(TIA)患者降纤、抗凝治疗的疗效.方法 选择173例TIA患者,进行ABCD2评分分层.根据治疗方案不同分为降纤组93例、抗凝组80例.比较两组7d内疗效、不同ABCD2评分分层下疗效及随访1年内结局.结果 降纤组治疗7d总有效率为87.10％,抗凝组为70.00％,两组比较P＜0.05.ABCD2评分4～5分的TIA患者采用两种治疗方案治疗3～7d,显效率比较有统计学意义(P＜0.05),随访1年时两组结局无统计学意义.结论 TIA发作后3～7d、ABCD2评分4～5分的患者使用降纤治疗较抗凝效果更好.%Objective To compare the therapeutic effectiveness of the defibrase and anticoagulant on transient ischemic attack (TIA) scored by different ABCD2. Methods 173 patients with TIA onset were selected and scaled by ABCD2. 93 cases received defibrase and the other 80 cases received anticoagulants. Patients were followed for one year. Results The total rate of availability is 87.10% in defibrase group within 7 days, while 70. 00% in anticoagulant group (P <0.05). For patients with an ABCD2 score of 4 to 5, a significant difference was observed between two treatments at the seconde result (P < 0.05 ). Defibrase was not superior to anticoagulants at one-year follow up. Conclusions Patients with TIA onset within 3 to 7 days and ABCD2 score within 4 to 5 would benefit more from defibrase than anticoagulants.
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