A diagnostic agent, use of diagnostic agent, composition, diagnostic kit, method of detection, imaging, or monitoring of the presence of matrix metalloproteinase.Pathological disorders associated with the activity of the same and asteriosclerose in one patient, method of identifying patients at high risk of stroke, transient ischemic attacks,,,Cardu00ecaca ischemia and acute myocardial infarction or death cardu00ecaca and method of image formation of simultaneous infusion cardu00ecaca and degradation of extracellular matrixes in a patient.

摘要

"Diagnostic agent, use of diagnostic agent, composition, diagnostic kit, method of detection, imaging, or monitoring of the presence of matrix metalloproteinase.Pathological disorders associated with the activity of the same, and atherosclerosis in a patient, method of identifying patients at high risk of stroke, transient ischemic attacks,Cardu00ecaca ischemia and acute myocardial infarction or death cardu00ecaca and method of image formation of simultaneous infusion cardu00ecaca and degradation of extracellular matrixes in a patient.The present invention relates to diagnostic agents, which include a diagnostic and a metal compound.In the compound comprises: a target 10 portions; a chelating agent; and one group of connection between the target and the chelating agent; in which the target portion is an inhibitor of matrix metalloproteinase.And in that the chelating agent is capable of combining to the metal of the diagnosis.The present invention also provides innovative compositions of the compounds of the present invention, kits and their use in the diagnosis of diseases associated with MMPs.