Objective To analyze the pulmonary function features of adult patients with mycoplasma pneumoniae pneumonia.Methods From November 2014 to October 2016 in Beijing Ditan Hospital Affiliated to Capital Medical University,a total of 30 patients with ordinary pneumonia were selected as A group,30 patients with mycoplasma pneumoniae pneumonia were selected as B group,30 healthy people admitted to this hospital for physical examination were selected as C group.Chest CT examination results and pulmonary function examination results of A group and B group were analyzed,index of pulmonary function was compared among the three groups,in mycoplasma pneumoniae pneumonia patients before and after treatment.Results (1)Chest CT examination results:21 cases of A group performed as plaque-like exudation(accounting for 70.0%),16 cases of B group performed as plaque-like exudation(accounting for 53.3%);pulmonary function examination results:19 cases of B group performed as normal pulmonary function(accounting for 63.3%),the major pulmonary dysfunction type was obstructive ventilatory dysfunction(accounting for 13.3%);13 cases of B group performed as normal pulmonary function(accounting for 43.3%),the major pulmonary dysfunction type was obstructive ventilatory dysfunction(accounting for 33.3%).(2)No statistically significant differences of VCmaxpred%,RVpred%,TLCpred%,VApred%,FVCpred% or PEFpred% was found among the three groups(P>0.05);VTpred% and MVVpred% of B group were statistically significantly higher than those of control group and A group(P<0.05);RV/TLCpred% and Rtotpred% of A group and B group were statistically significantly higher than those of control group,while FEV1pred%,FEV1/FVCpred%,MEF25pred%,MEF50pred%,MEF75pred%,MMEF75/25pred% and DLCO-SBpred% of A group and B group were statistically significantly lower than those of control group(P<0.05).(3)No statistically significant differences of VTpred%,RVpred%,TLCpred%,RV/TLCpred%,MVVpred% or DLCO-SBpred% was found in mycoplasma pneumoniae pneumonia patients before and after treatment(P>0.05);after treatment,VCmaxpred%,VApred%,FEV1pred%,FVCpred%,FEV1/FVCpred%,PEFpred%,MEF25pred%,MEF50pred%,MEF75pred% and MMEF75/25pred% of patients with mycoplasma pneumoniae pneumonia were statistically significantly higher than those before treatment,while Rtotpred% of patients with mycoplasma pneumoniae pneumonia was statistically significantly lower than that before treatment(P<0.05).Conclusion Mycoplasma pneumoniae pneumonia patients exist airway limitation,mainly performed as ventilatory dysfunction,diffusion dysfunction and elevated airway resistance,while anti-infective therapy can effectively improve the pulmonary function;the difference of pulmonary function is not significant between ordinary pneumonia and mycoplasma pneumoniae pneumonia.%目的 分析成年肺炎支原体肺炎患者的肺功能特点.方法 选取2014年11月-2016年10月在首都医科大学附属北京地坛医院住院及门诊就诊的普通肺炎患者30例(A组)、MPP患者30例(B组),另选取同期体检健康者30例作为对照组.分析A组和B组患者胸部CT检查结果及肺功能检查结果,比较3组受试者肺功能指标及MPP患者治疗前后肺功能指标.结果 (1)胸部CT检查结果:A组和B组患者均以斑片渗出样改变为主,分别占70.0%、53.3%.肺功能检查结果:A组患者肺功能正常者占63.3%,肺功能障碍主要表现为阻塞性通气功能障碍,占13.3%;B组患者肺功能正常者占43.3%,肺功能障碍主要表现为阻塞性通气功能障碍,占33.3%.(2)3组受试者最大肺活量占预计值百分比(VCmaxpred%)、残气量占预计值百分比(RVpred%)、肺总量占预计值百分比(TLCpred%)、肺泡通气量占预计值百分比(VApred%)、用力肺活量占预计值百分比(FVCpred%)、呼气峰值流速占预计值百分比(PEFpred%)比较,差异均无统计学意义(P>0.05);B组患者潮气量占预计值百分比(VTpred%)和最大通气量占预计值百分比(MVVpred%)高于对照组和A组(P<0.05);A组和B组患者残气量与肺总量比值占预计值百分比(RV/TLCpred%)、气道阻力占预计值百分比(Rtotpred%)高于对照组,第1秒用力呼气容积占预计值百分比(FEV1pred%)、第1秒用力呼气容积与用力肺活量比值占预计值百分比(FEV1/FVCpred%)、25%肺活量用力呼气流速占预计值百分比(MEF25pred%)、50%肺活量用力呼气流速占预计值百分比(MEF50pred%)、75%肺活量用力呼气流速占预计值百分比(MEF75pred%)、最大呼气中段流速占预计值百分比(MMEF75/25pred%)及一口气一氧化碳弥散量占预计值百分比(DLCO-SBpred%)低于对照组(P<0.05).(3)MPP患者治疗前后VTpred%、RVpred%、TLCpred%、RV/TLCpred%、MVVpred%及DLCO-SBpred%比较,差异均无统计学意义(P>0.05);治疗后VCmaxpred%、VApred%、FEV1pred%、FVCpred%、FEV1/FVCpred%,PEFpred%、MEF25pred%、MEF50pred%、MEF75pred%及MMEF75/25pred%高于治疗前,Rtotpred%低于治疗前(P<0.05).结论 MPP患者存在气流受限,主要表现为通气功能、弥散功能障碍及气道阻力增加,而抗感染治疗可有效改善患者肺功能;MPP和普通肺炎患者肺功能无明显差异.
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