骨韧带样纤维瘤临床病理观察

摘要

Objective: To investigate the clinico - pathological characteristics and differential diagnosis of desmo-plastic fibroma of bone. Methods: A case with desmoplastic fibroma of costal bone was studied by microscopic observation and immunohistochemical staining. Results: Desmoplastic fibroma of bone contains myofibroblasts. Immuno-histochemical staining showed that the tumor cells were positive for vimentin, partially for actin and SMA, but negative for S - 100, CD34, CD57, NF. Conclusion: Desmoplastic fibroma of bone is a rare tumor. The diagnosis should be differented from other mesenchymal tumors of bone.%目的:探讨骨韧带样纤维瘤的临床病理特征.方法:通过光镜及免疫组化方法对1例肋骨韧带样纤维瘤进行观察,同时复习相关文献.结果:骨韧带样纤维瘤瘤细胞由成纤维细胞组成.免疫组化:肿瘤细胞Vimentin弥漫阳性,actin、SMA部分阳性、S-100、CD34、CD57、NF均阴性.结论:骨的韧带样纤维瘤是一种罕见肿瘤,需与骨其它间叶性肿瘤鉴别.