α-1，6岩藻糖基转移酶与甲胎蛋白异质体在原发性肝癌诊断中的应用

摘要

目的：分析α-1，6岩藻糖基转移酶（FUT8）与甲胎蛋白异质体（AFP - L3）在原发性肝癌（PLC）诊断中的应用价值。方法：采用酶联免疫吸附试验（ELISA）方法分别检测我院92例 PLC 患者和42例非原发肝癌（NPLC）患者血清中 FUT8和 AFP - L3。结果：经统计学分析，PLC 组与 NPLC 组血清 FUT8和 AFP - L3比较差异有统计学意义（P ﹤0.05）。结论：α-1，6岩藻糖基转移酶（FUT8）与甲胎蛋白异质体（AFP - L3）在原发性肝癌（PLC）诊断中有一定的应用价值。%To study the value of α - 1,6 - fucosyltransferase and alpha - fetoprotein variant in diagno-sis of the primary liver cancer(PLC). Methods:By using enzyme linked immunosorbent assay(ELISA),detecting the FUT8 and AFP - L3 in sera of 92 cases of PLC patients and 42 cases of non - primary liver carcinoma(NPLC). Re-sults:Through statistical analysis,serum FUT8 and AFP - L3 had significant difference between PLC group and NPLC group(P ﹤ 0. 05). Conclusion:α - 1,6 - fucosyltransferase and alpha - fetoprotein variant have some value in the di-agnosis of primary liver cancer(PLC).