Objective To explore the clinical feature of children with Takayasn's arteritis (TA), and to analyze the relevant treatment methods and prognosis. Methods Retrospective analysis was performed on the clinical manifestations of 25 children with TA, and the process of treatment and prognosis. Results In this study, the ratio of male to female was 8 : 17, and the average onset age was ( 10.8 ± 3.0) years old. The most common TA type was 1 (56.0%), and the initial symptoms included headache, convulsions, fatigue, protcinuria, etc. All children had high blood pressure and 19 cases had lo (Tubercle bacillus) injection, 22 cases received cortjcosterojcis, and/or eveiophos-pharnide treatment All patient's condition relieved, but 16 patients had recurrence. Three cases received interventional therapy, no stenosis happened again. Conclusions For children, especially adolescent children with headache and high blood pressure as the main clinical manifestation, the diagnosis of TA should be kept in mind, TA in children is often caused by tuberculosis infection, therefore, early diagnosis and treatment of tuberculosis infection can effectively prevent the occurrence of TA. Drug treatment have a higher recurrence rate, interventional therapy can effectively improve ischemic symptoms.%目的 探讨儿童多发性大动脉炎(TA)的临床特征,分析相关治疗方法和转归.方法回顾性分析25例儿童多发性大动脉炎患儿的临床表现、治疗过程及预后.结果 患儿发病年龄为(10.8±3.0)岁,男女比为8:17.TA临床分型中以Ⅲ型最多(56.0%),常以头痛、抽搐、乏力、蛋白尿等为首发症状,25例患儿均有高血压,其中19例有结核感染.22例患儿接受糖皮质激素和(或)环磷酰胺治疗后病情缓解,其中16例出现复发;3例患儿接受血管内介入治疗,效果良好,未再出现狭窄.结论 儿童尤其是青春期以头痛、高血压为主要表现时需注意多发性大动脉炎可能.儿童多发性大动脉炎常由结核感染引起,因此早期发现与治疗结核感染可有效避免该病的发生.药物治疗儿童TA 复发率较高,介入治疗能有效改善缺血症状.
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