儿童支气管哮喘急性发作的病原分布特点

摘要

Objective To investigate the distribution of etiological agents in children with asthma exacerbation in Chongqing.Methods Two hundred and three cases of hospitalized children ( age ≥ 5 years) with asthma exacerbation from November 2007 to October 2008 in Children's Hospital of Chongqing Medical University were retrospectively analyzed.Results Among children with asthma attack, the positive rate of Chlamydia pneumoniae ( CP )and Mycoplasma pneumoniae ( Mp ), was respectively 29.6％ and 22.9％; The percentage of 7 common respiratory viruses ( including respiratory syncytial virus (RSV), Adenovirus, Influenza virus A, B, Parainfluenza virus 1, 2,3 ) in children with asthma attack was 10.2％.RSV accounted for 4.5％ among patients.The window time of respiratory tract infection-induced asthma attack was primarily determined in 4.2 ± 3.1 days.Conclusions Asthma exacerbation in children is closely related to MP, CP or respiratory viruses infection, but the positive rates of 7 common respiratory tract viruses are low.%目的 了解重庆地区儿童支气管哮喘急性发作的病原分布特点.方法 回顾性分析重庆医科大学附属儿童医院2007年11月至2009年10月收治的203例5岁及以上支气管哮喘急性发作住院患儿临床资料.结果 哮喘急性发作患儿肺炎衣原体(CP)检出率为29.6%、肺炎支原体(MP)检出率为22.9%;7种呼吸道病毒检出阳性率为10.2%,其中RSV占4.5%,居病毒检出率首位.哮喘患儿呼吸道感染诱导哮喘的发作窗为(4.2±3.1)d.结论 重庆地区5岁及以上儿童哮喘急性发作与呼吸道病毒、MP、CP感染密切相关,且常见的7种呼吸遭病毒检出率低.