Crystal Structure and Biological Activities of N-(5-(4-Chloro-2-(trifluoromethyl)phenyl)furan-2-carbonyl)-N'-(4,6-dimethylpyrimidin-2-yl)thiourea

摘要

The new title compound N-(5-(4-chloro-2-(trifluoromethyl)phenyl)furan-2-carbon-yl)- N'-(4,6-dimethylpyrimidin-2-yl)thiourea (C19H14ClF3N4O2S) has been synthesized, and its crystal structure and biological behaviors were studied. The title compound crystallizes in the monoclinic system, space group P21/c with a = 7.932(5), b = 33.46(2), c = 7.556(5) (A),β=98.058(9) °,V = 1986(2)(A)3, Mr = 454.85, Z=4, Dc=1.521 g/cm3, μ= 0.349 mm-1 and F(000) = 928. The structure was solved by direct methods and refined to R = 0.0724 and wR = 0.1429 for 3494 observed reflections (I > 2s(I)). Intermolecular hydrogen bonds along the b axis together with the continuous π-πinteractions construct the three-dimensional architecture of the title compound. The preliminary biological tests show definite herbicidal activity for the title compound.