成年男性SPECT心肌灌注显像左心室下后壁衰减伪影与体质量指数的相关性分析

摘要

Objective To evaluate the relationship between attenuation artifacts on inferior-posterior wall of left ventricle in 99mTc-MIBI myocardial perfusion SPECT and body mass index (BMi) of adult males. Methods Totally 76 male patients underwent 99mTc-MIBI myocardial perfusion SPECT in the supine and prone position. Radioactive count and area of perfusion defect on the inferior-posterior wall of left ventricle in two positions were calculated with bull's eye. Then the differences were compared and the correlations to BMI were analyzed. Perfusion defect degree in the supine position and filling degree in the prone position were scored and compared between different BMI patients. Results There were 43 normal weight cases and 33 overweight cases. In the supine position, the radioactive count of inferior-posterior wall was significant higher (P<0. 001) and the perfusion defect areas was significant lower than in the prone position (P<0. 001), which were not related to BMI (both P>0. 05). There was no significant difference on the radioactive count and perfusion defect area between different BMI groups (both P>0. 05). Perfusion defect on the inferior-posterior in the supine position could be improved in the prone position, there was no significant difference on the scores of defect and filling degree between normal different BMI groups (both P>0. 05). Conclusion There is no relation between attenuation artifacts on inferior-posterior wall of left ventricle in myocardial perfusion SPECT and BMI in adult males. The attenuation artifacts in the supine position can be obviously improved in the prone position, which is not related to BMI.%目的 探讨成年男性SPECT心肌灌注显像左心室下后壁衰减程度与体质量指数(BMI)的相关性.方法 对成年男性患者76例行仰卧位和俯卧位99mTc-MIBI心肌灌注显像,重建两种体位下的心肌断层图像,利用靶心图获得两种体位显像左心室下后壁的放射性计数和灌注缺损面积,比较二者差异及其与BMI的相关性；对仰卧位显像时左心室下后壁的灌注缺损程度和俯卧位显像时的填充程度进行评分,比较不同体质量组之间评分的差异.结果 76例中,体质量正常组43例,体质量超重组33例.俯卧位显像时左心室下后壁的平均放射性计数显著高于仰卧位(P＜0.001),平均灌注缺损面积显著低于仰卧位(P＜0.001),两种显像体位间放射性计数及灌注缺损面积的差异与BMI无相关性(P均＞0.05)；仰卧位和俯卧位显像时左心室下后壁的平均放射性计数和灌注缺损面积在不同体质量组间差异无统计学意义(P均＞0.05).仰卧位显像左心室下后壁稀疏缺损区在俯卧位显像时均可见不同程度的填充,缺损和填充程度评分在不同体质量组间的差异无统计学意义(P均＞0.05).结论 成年男性在仰卧位显像时,左心室下后壁的衰减程度与BMI无相关；俯卧位显像能明显改善男性患者左心室下后壁的衰减伪影,但改善程度与BMI无相关.