磁敏感加权成像技术在大面积脑梗死急性期的临床相关性研究

摘要

Objective This paper aims to analyze the characteristics and clinical relevance of thrombus in patients with acute cerebral infarction at a large area by magnetic susceptibility weighted imaging (SWI). Methods From January 2015 to January 2017, a total of 80 patients with acute cerebral infarction in our hospital were enrolled in the study (clinical symptoms<48 h). The patients were treated with SWI and corresponding national institutes of health stroke scale (NIHSS) score was followed up at 2 and 3 months. Results SWI showed a significant correlation between NIHSS score and clinical outcome after acute cerebral infarction (r=-0.829, P=0.000); the comparison in NIHSS score and bleeding severity, (r=0.779, P=0.000), (r=0.688, P=0.003), (r=0.889, P=0.000), had relevance. SWI showed that acute cerebral infarction and acute NIHSS score change (r=-0.672, P=0.002). SWI showed a significant correlation between thrombus length and clinical NIHSS score (r=-0.699, P=0.001) in acute cerebral infarction; there was also a significant correlation between NIHSS score and clinical outcome (r=-0.642, P=0.003). Conclusion SWI is specificity and sensitivity to intravascular thrombosis in large area acute cerebral infarction, which is of great clinical significance for the diagnosis of acute cerebral infarction. It has great clinical significance for clinical treatment and prognosis evaluation.%目的 通过磁敏感加权成像(Susceptibility Weighted Imaging,SWI)技术分析大面积脑梗死急性期患者血栓的特点及临床相关性.方法 选取2015年1月~2017年1月间,在我院治疗的80例大面积脑梗死急性期患者作为研究对象(临床症状<48 h),进行SWI,并计算得出相应的美国国家健康研究所脑卒中分级量表(NIHSS)评分,在第2周和3个月进行随诊.结果 SWI显示大面积脑梗死急性期后出血与临床NIHSS评分改变具有相关性(r=-0.829,P=0.000);NIHSS评分按分等级与出血程度相关性比较,分别为(r=0.779,P=0.000),(r=0.688,P=0.003),(r=0.889,P=0.000),具有相关性;SWI显示大面积脑梗死急性期血栓部位与临床NIHSS评分改变也具有相关性(r=-0.672,P=0.002);SWI显示大面积脑梗死急性期血栓长度与临床NIHSS评分改变也具有相关性(r=-0.699,P=0.001);SWI显示大面积脑梗死急性期侧枝血管与临床NIHSS评分改变也具有相关性(r=-0.642,P=0.003).结论 SWI对大面积脑梗死急性期血管内血栓具有特异性和敏感性,对大面积脑梗死急性期的诊断具有临床意义,对于临床治疗和预后评估具有较大的临床意义.