DNA金属化及其应用

摘要

While the intrinsic conductivity of DNA duplex is still under controversy, DNA metallization becomes a promising way to achieve enhanced conductivity of DNA and thus is the key to its applications in nanoelectronics. This review summarizes recent methodological developments in the metallization of DNA including electrostatic adsorption, electroless deposition, DNA self-assembly and metal evaporation. Some typical applications of metallized DNA in catalysis,sensing, nanodevices and nanoelectronics were introduced. Future challenges and promises of this field are also discussed.%由于DNA自身的导电性尚存在争议,研究人员试图通过金属化途径来提高DNA双螺旋结构的导电性,从而使其能够在纳米电子学方面发挥重要作用.本文简要综述了静电吸附,无电沉积,DNA自组装、金属蒸镀等常用的DNA金属化方法,介绍了这些金属化DNA结构在纳米电子学、催化、传感等相关领域的应用,在此基础上对DNA金属化技术的进一步发展和存在的挑战进行了展望,揭示了其广阔的基础和应用研究前景.