肿瘤热疗与肿瘤免疫在转化医学中的研究进展

摘要

肿瘤热疗成为继手术、放疗、化疗和生物治疗后又一重要的肿瘤治疗手段.热休克蛋白及树突状细胞受热疗影响较大并与肿瘤免疫密切相关,逐渐受到基础研究及临床应用的重视.通过这些研究,热疗联合肿瘤免疫治疗逐渐成为转化医学中的研究重点,这一新的概念有希望改变现有的肿瘤治疗策略.%Thermotherapy becomes another important cancer treatment apart from the surgery, radiotherapy, chemotherapy and biological therapy. Heat shock proteins and dendritic cells which influenced by hyperthermia, correlate with tumor immunology, and was studied from bench to bedside. According to these researches, the development of translational medicine in combination of thermotherapy and tumor immunology has been in concern, and may change the status in quo of the treatment of cancer.