Objective To investigate the efficacy and postoperative complications of total endoscopic thyroidectomy for treating thyroid carcinoma. Methods One hundred and twenty patients with thyroid cancer were enrolled in department of thyroid surgery,henan Prov-ince People′s Hospital,from June 2011 to June 2013 and patients were randomly assigned into observation group(n = 60) and control group(n = 60) according to the random number table. The control group was treated with radical thyroidectomy and observation group underwent total endoscopic thyroidectomy. The operation and postoperative complications of two groups were compared. The patients were followed up for 3 years. The survival rate,recurrence rate and distant metastasis rate of the two groups were observed. Results Two groups of patients were successfully completed surgery. The postoperative hospital stay of observation group was shorter than control group,the difference was statistically significant(P < 0. 05). The bleeding volume and postoperative drainage volume were less than those in the control group,the VAS score after operation 24 h was lower than the control group,the difference was statistically significant (P < 0. 05),while the operation time of two groups was not statistically significant(P > 0. 05). The incidences of hypothyroid parathy-roid hormone and hypocalcemia of observation group were lower than control group,the differences were statistically significant(P < 0. 05),but dysphonia,numbness of hand,foot and hoarseness of two groups were no statistically significant difference(P > 0. 05). The 1-year survival rate,2-year survival rate,3-year survival rate,recurrence rate and distant metastasis rate of the two groups were not statisti-cally significant(P > 0. 05). Conclusions The total curative effect of radical thyroidectomy is similar to that of conventional neck thy-roid carcinoma. Meanwhile,radical resection of thyroid carcinoma combined with total endoscopy can reduce the incidences of low para-thyroid hormone and hypocalcemia.%目的 探讨全腔镜下甲状腺癌根治术对甲状腺癌疗效及术后并发症的影响.方法 选取120例甲状腺癌患者,根据随机数字表法将患者分为观察组(n=60)和对照组(n=60),对照组应用传统甲状腺癌根治术,观察组行全腔镜下甲状腺癌根治术,比较两组患者手术情况及术后并发症情况.术后对两组随访3年,观察两组生存率、复发率及远处转移率情况.结果 两组患者均成功完成手术,观察组术后住院时间短于对照组,术中出血量、术后引流量少于对照组,术后24 h视觉模拟评分(VAS)低于对照组,差异有统计学意义(P<0.05),两组手术时间比较,差异无统计学意义(P>0.05).观察组术后低甲状旁腺激素血症、低血钙症发生率低于对照组,差异有统计学意义(P<0.05),两组发音困难、手足麻木、声音嘶哑比较,差异无统计学意义(P>0.05).两组患者1、2、3年存活率、复发率及远处转移率比较,差异无统计学意义(P>0.05).结论 全腔镜下甲状腺癌根治手术临床疗效与传统甲状腺癌根治术相当,但全腔镜下甲状腺癌根治手术对患者创伤小,可降低低甲状旁腺激素血症、低血钙症的发生.
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