首页> 外文学位 >Primerjava napovedne vrednosti rezultatov lestvic RISC (Revised Injury Severity Classification) in TRISS (Trauma and Injury Severity Score) na slovenskem vzorcu hudo poskodovanih.
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Primerjava napovedne vrednosti rezultatov lestvic RISC (Revised Injury Severity Classification) in TRISS (Trauma and Injury Severity Score) na slovenskem vzorcu hudo poskodovanih.

机译:在严重受伤的斯洛文尼亚样本上,RISC(修订的损伤严重度分类)和TRISS(创伤和损伤严重度评分)量表的预测值的比较比较。

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摘要

BACKGROUND: The fundamental condition for ensuring the quality of treatment is monitoring the results. For an objective assessment, proper data is required. The main purpose of trauma registries is to gather data on the complete course from the accident site to the completion of therapy. Because of the dispersion of trauma patients across multiple hospitals in Slovenia, a national major trauma registry is being considered for implementation. The TRISS methodology is most commonly used to compare treatment results to international standards. It was developed using a multivariate analysis of a trauma patient group (MTOS), which significantly differs from the Slovenian pattern of major trauma incidents. Because of this, the usefulness of the TRISS methodology has come under doubt. After including Slovenian trauma patients in the German Traumaregistry (TR DGU), we have implemented the RISC method for comparing treatment results with other centres. The new method has not yet been evaluated on a patient group which differs from the TR DGU pattern. The objective of the study is to assess the usefulness of the RISC method on the Slovenian pattern of major trauma patients and to compare it to the TRISS method.;METHODS: Since the inclusion in the TR DGU in 2006, we have been prospectively gathering data on a cohort group of 376 major trauma patients at General Hospital Celje and sent it to the TR DGU. We have compared risk factors between trauma patients at General Hospital Celje and the TR DGU and calculated the TRISS and RISC score for every patient. The M-statistic was used to compare the distribution of probability of survival between General Hospital Celje, MTOS and TR DGU. TRISS, RISC and RISC II were evaluated using the statistical methods of discrimination (aROC), precision (difference in survival) and calibration (H-L Statistic).;RESULTS: The average age of patients was 47 years, 83% of them were men, 95% had blunt trauma. The average ISS was 26,4 (90% ≥16). Their in-hospital mortality rate was 17,5%. The standardized mortality rate has shown a 1,9% lower mortality than predicted with statistical models.;A significant discrepancy in risk factors between trauma patients at General Hospital Celje and the TR DGU was discovered, which can be attributed to different inclusion criteria. The Slovenian sample of major trauma patients was confirmed to be different, as was the need to evaluate the effectiveness of the RISC method.;We have compared survival rates between patient groups and found a poor match between the patient group at General Hospital Celje and the MTOS group (M=0,50) and a good match with TR DGU (M=0,88). The distribution at General Hospital Celje has not changed significantly between the periods of 2006--07 and 2011--12 (M=0,90). We have confirmed a significant difference between the General Hospital Celje and the MOTS patients groups, which affects the usefulness of the TRISS method. We have confirmed a good match of results between the General Hospital Celje and the TR DGU patient groups, despite differences in risk factors, which justifies the use of the RISC method on the Slovenian pattern of major trauma patients.;The RISC and RISCII scores have shown the best discrimination (aROC 0,91 and 0,90). The RISC score was the most precise (difference in mortality rate of 1,9%) and also had the best and almost perfect calibration (H-L 0,53).;CONCLUSIONS: The RISC method was shown to have better discrimination, calibration and precision than the TRISS methodology for the Slovenian pattern of major trauma patients. The comparison of data at General Hospital Celje between 2006--07 and 2011--12 has shown a few differences. The improvement is best seen with indicators of treatment quality (shorter prehospital time, shorter ER time). These differences have not affected the usefulness of the RISC method, however. It has stood the test of time, as the structure and treatment of patients have changed. The TRISS method, despite new coefficients, is not suitable for the Slovenian pattern of major trauma patients. The updated RISCII is a good method, although not any better than the established RISC method.
机译:背景:确保治疗质量的基本条件是监测结果。为了进行客观评估,需要适当的数据。创伤登记的主要目的是收集从事故现场到治疗完成的整个过程的数据。由于斯洛文尼亚的创伤患者分散在多家医院中,因此正在考虑实施全国重大创伤登记系统。 TRISS方法最常用于将治疗结果与国际标准进行比较。它是通过对创伤患者组(MTOS)进行多变量分析而开发的,这与重大创伤事件的斯洛文尼亚模式有显着差异。因此,TRISS方法的有效性一直受到质疑。在将斯洛文尼亚创伤患者纳入德国创伤登记局(TR DGU)之后,我们实施了RISC方法以将治疗结果与其他中心进行比较。与TR DGU模式不同的患者组尚未评估新方法。该研究的目的是评估RISC方法在主要创伤患者的斯洛文尼亚模式中的有效性,并将其与TRISS方法进行比较。方法:自2006年纳入TR DGU以来,我们一直在前瞻性地收集数据在Celje综合医院的376名主要外伤患者队列中,将其发送给TR DGU。我们比较了Celje总医院创伤患者和TR DGU之间的危险因素,并计算了每位患者的TRISS和RISC评分。 M统计量用于比较总医院Celje,MTOS和TR DGU之间的生存概率分布。结果:患者的平均年龄为47岁,其中83%为男性,其平均年龄为47岁。 95%的患者受到钝器伤。 ISS平均为26.4(90%≥16)。他们的院内死亡率为17.5%。标准化死亡率显示比统计模型预测的死亡率低1.9%。;发现Celje综合医院创伤患者与TR DGU之间的危险因素存在显着差异,这可以归因于不同的纳入标准。斯洛文尼亚主要创伤患者的样本被证实是不同的,评估RISC方法的有效性也是如此。我们比较了患者组之间的生存率,发现Celje综合医院的患者组与MTOS组(M = 0,50)与TR DGU良好匹配(M = 0,88)。在2006年7月7日至2011年12月12日之间,采列综合医院的分布没有太大变化(M = 0.90)。我们已经证实,总医院Celje与MOTS患者组之间存在显着差异,这影响了TRISS方法的有效性。尽管风险因素存在差异,但我们已经确认总医院Celje和TR DGU患者组之间的结果很好匹配,这证明在严重创伤患者的斯洛文尼亚模式中使用RISC方法是合理的; RISC和RISCII得分为显示出最好的辨别力(aROC为0.91和0.90)。 RISC评分是最精确的(死亡率差异为1.9%),并且具有最佳和几乎完美的校准(HL 0,53)。;结论:RISC方法具有更好的辨别力,校准和精度比采用TRISS方法进行的重大创伤患者的斯洛文尼亚模式。比较2006年7月7日至2011年12月12日塞利综合医院的数据时,发现了一些差异。从治疗质量的指标(住院前时间短,ER时间短)可以看出这种改善。但是,这些差异并未影响RISC方法的实用性。随着患者结构和治疗方式的变化,它经受了时间的考验。尽管有了新的系数,TRISS方法仍不适用于主要创伤患者的斯洛文尼亚模式。更新的RISCII是一个很好的方法,尽管没有比建立的RISC方法更好。

著录项

  • 作者

    Brilej, Drago.;

  • 作者单位

    Univerza v Mariboru (Slovenia).;

  • 授予单位 Univerza v Mariboru (Slovenia).;
  • 学科 Medicine.
  • 学位 Ph.D.
  • 年度 2014
  • 页码 99 p.
  • 总页数 99
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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