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Assessment of lamb wave dispersion in cornea using shear wave imaging optical coherence tomography (SWI-OCT)

机译:使用剪切波成像光学相干断层扫描(SWI-OCT)评估角膜中的兰姆波散布

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The characteristics of lamb wave propagation in cornea can be of great importance for the quantitative measurement of corneal viscoelasticity. Here, we report the use of shear wave imaging optical coherence tomography (SWI-OCT) to assess the dispersion of lamb wave propagation in an ex vivo rabbit cornea. The temporal displacement profile of lamb wave propagation is obtained with SWI-OCT. From the spectral analysis on the corneal lamb wave, the phase information of the wave propagation can be extracted, which is used to quantify the phase velocity at different frequencies. The dependence of the phase on the propagation distance is presented with 2-D depth-resolved mapping at typical frequency components with micro-scale spatial resolution. Results indicate that the obtained lamb wave dispersion curve agrees well with the analytical approximation and demonstrate the feasibility of using SWI-OCT to study the dispersion of lamb wave propagation in cornea.
机译:兰姆波在角膜中传播的特征对于定量测量角膜粘弹性可能非常重要。在这里,我们报告使用剪切波成像光学相干断层扫描(SWI-OCT)来评估羊波在离体兔角膜中传播的分散性。用SWI-OCT获得了兰姆波传播的时间位移轮廓。从对角膜兰姆波的频谱分析中,可以提取出波传播的相位信息,用于量化不同频率下的相速度。相位与传播距离的相关性通过二维深度解析映射在具有微尺度空间分辨率的典型频率分量上表示。结果表明,所得到的兰姆波色散曲线与解析近似吻合得很好,并证明了使用SWI-OCT研究兰姆波在角膜中传播的色散的可行性。

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