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Volumetric vessel reconstruction method for absolute blood flow velocity measurement in Doppler OCT images

机译:多普勒OCT图像绝对血流速度测量的容积血管重建方法

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摘要

We demonstrated the fully distributed measurement of absolute blood flow velocity for the middle cerebral artery by reconstructing the vessel geometry using pure DOCT stack images. The algorithm automatically localizes the vessel lumens, calculates the Doppler angle, and then quantifies the absolute BFV on each position of the whole MCA. Our approach is verified by quantifying the hemodynamics of cerebral arteries of resting state rodents with custom-built, swept-source optical coherence tomography.
机译:我们通过使用纯DOCT堆栈图像重建血管几何结构,演示了大脑中动脉绝对血流速度的完全分布式测量。该算法自动定位血管腔,计算多普勒角度,然后在整个MCA的每个位置上量化绝对BFV。我们的方法通过用定制的扫频光学相干断层扫描定量静息态啮齿动物的脑动脉血流动力学而得到验证。

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    Beckman Laser Institute, University of California, Irvine, Irvine, CA 92612, USA,Institute of Optical Communication Engineering, Nanjing University, Nanjing, Jiangsu, 210093, China,Current address: Guangdong Provincial Key Laboratory of Biomedical Image Processing and School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510900, China;

    Beckman Laser Institute, University of California, Irvine, Irvine, CA 92612, USA;

    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, 92697, USA,The Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA, 92697, USA;

    Beckman Laser Institute, University of California, Irvine, Irvine, CA 92612, USA;

    Institute of Optical Communication Engineering, Nanjing University, Nanjing, Jiangsu, 210093, China;

    Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697, USA,Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, 92697, USA,The Center for the Neurobiology of Learning and Memory, University of California, Irvine, Irvine, CA, 92697, USA;

    Beckman Laser Institute, University of California, Irvine, Irvine, CA 92612, USA,Department of Biomedical Engineering, University of California, Irvine, Irvine, CA 92697, USA;

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