Volumetric vessel reconstruction method for absolute blood flow velocity measurement in Doppler OCT images

摘要

We demonstrated the fully distributed measurement of absolute blood flow velocity for the middle cerebral artery by reconstructing the vessel geometry using pure DOCT stack images. The algorithm automatically localizes the vessel lumens, calculates the Doppler angle, and then quantifies the absolute BFV on each position of the whole MCA. Our approach is verified by quantifying the hemodynamics of cerebral arteries of resting state rodents with custom-built, swept-source optical coherence tomography.