NanoBio-Tools for Selective Activation of Toll-like receptors (TLRs)

摘要

The immobilization of polyinosinic-polycytidylic acid [poly(I:Q] on Y-Fe2O3 nanoparticles via the phosphor-amidate route using a multifunctional polymer is reported The dsRNA coupled nanopaiticles were used to visualize the Toll-like (TLR3) receptors at the cell surface, The presence of TLR3 was demonstrated independently in the Caki-1 cell line by RT-PCR and immunostaining techniques.