ANALYSIS OF CLINICAL PLATELET FUNCTION OF DOGS CATS

摘要

Platelets are anucleate, disc-shaped, cytoplasmic fragments that play an essential role in primary hemostasis, the initiation of a platelet plug, and the preservation of vascular integrity. Platelets are the smallest cellular component in the blood. Platelets circulate as small discs along the vessel edge. The exterior surface is highly reactive to external stimuli, ready to undergo a shape change to facilitate hemostasis on the damaged endothelial surface. Placed near the site of initial response tovascular injury, platelets react to stimuli, alter their shape, spread and adhere to the endothelium (and each other), secrete their granular contents (e.g. ADP, serotonin) to amrjlifv the response, and interact with the hemostatic svstem to bind fibrinogen (to GP Ilbllla) and solidify into a fibrin clot.