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The Effects of PACAP and VIP on the in Vitro Melatonin Secretion from the Embryonic Chicken Pineal Gland

机译:PACAP和VIP对胚胎鸡松弛腺体体外褪黑素分泌的影响

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The effects of in vitro VIP administration and those of in ovo pretreatment with PACAP antagonist (PACAP6-38) on the development of the embryonic melatonin (MT) secretion were investigated. With dy-namic in vitro bioassay we showed that (1) the development of the circa-dian MT secretion seems to be unaffected by VIP administrations or by PACAP6-38 pretreatments; (2) exposure of the embryonic chicken pineal gland to VIP induces transitory increase in MT secretion at or before the 14th embryonic day in vitro.
机译:研究了体外VIP施用的影响与PACAAP拮抗剂(PACAP6-38)对胚胎褪黑素(MT)分泌的发育的卵子预处理的影响。随着Dy-namic体外生物测定的,我们表明(1)大约MT分泌的发展似乎不受VIP主管部门或Pacap6-38预处理的影响; (2)胚胎鸡松弛腺暴露于VIP在体外14末端胚胎日或之前的MT分泌中诱导暂时增加。

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