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Large Scale Analysis of Transcriptional and Translational Control Mechanism in Human Ribosomal Proteins

机译:人核糖体蛋白转录和翻译控制机制的大规模分析

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The human 80S ribosome was composed with 79 ribosomal proteins (RPs) and 4 rRNAs. Although all of RP genes have been thought to have an identical transcriptional and translational control mechanism, no comprehensive observation has been conducted for understanding RP gene expression mechanism. As more than 2,000 RP related pseudogenes have been reported to exist in Human Genome [5], all 79 set of RP gene data, which pseudogenes and sequencing errors were excluded by manual procedure, were used for this analysis. Here we describe the diversity of transcriptional and translational control mechanism in RP genes.
机译:人80S核糖体由79个核糖体蛋白(RPS)和4 rRNA组成。尽管所有RP基因都被认为具有相同的转录和翻译控制机制,但没有对理解RP基因表达机制进行综合观察。由于据报道,在人类基因组中存在超过2,000rp相关的假生素[5],所有79组RP基因数据,用手动程序排除了Pseudogenes和测序误差,用于该分析。在这里,我们描述了RP基因转录和翻译控制机制的多样性。

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