Enhancing Functional Cohesiveness in Renal Dynamic Contrast Enhanced-Magnetic Resonance Imaging (DCE-MRI) by Extraction of Glomerulus Kinetics

摘要

Based on the kinetic parameters from Tofts DCE model, permeability and volume constant, we classified renal cortex and medulla into four distinct types of tissue (type Ⅰ to Ⅳ). Type Ⅰ tissue is identified as glomeru-lus-rich tissue and hence its tracer kinetic curve is fitted into the Baumann and Rudin model to yield a more specific measurement of glomerular function.