Delft University of Technology, PO BOX 5048, 2600 GA Delft,the Netherlands. E-mail: J.Q.J.C.Verberk@TUDelft.nl, phone: +31152785838

摘要

On-line solid phase extraction (SPE) was coupled to liquid chromatography with tandemmass spectrometry (LC/MS/MS) to detect 19 compounds from diverse group ofpharmaceuticals, pesticides, personal care products and steroids at concentration as low asng L~(-1) in drinking and surface waters was studied. All results displayed a good degree ofreproductibility, with relative standard deviations (RSD) of less than 12 % for allcompounds. Matrix effects were observed for some compounds without exceeding morethan 25%. Method detection limits were in the range of 2 to 25 ng L~(-1) except for estriolwith a value of 50 ng L~(-1). The recoveries varied from 87 to 110 % in surface waters. Theanalysis of various water samples with the detection and quantification of some ofselected compounds were also reported. This method was preferred over traditional offlineprocedures since it can minimize tedious sample preparation and increasesproductivity.