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Using Qualitative Technology for Modeling the Process of Virus Infection

机译:使用定性技术对病毒感染过程进行建模

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摘要

The quantitative analysis of viral infection dynamical model can't be processed easily due to the lack of complex quantitative knowledge in such biological system; therefore, the methods based on qualitative analysis become an alternative solution to researches in the complicated biological process. In this paper the qualitative technology is introduced to model and analyze the process of virus entry. A rough model is proposed first to be the foundation of further research. With more knowledge in the process, the framework is expanded by inserting the qualitative description of different kinds of factors that have interactive influence on the process of virus entry. The factors are described qualitatively in influencing degree, and the qualitative model is built based on the interaction among these influencing factors and the viruses and cells. The judging matrices are constructed according to the qualitative model and the coherence of these matrices is verified. A qualitative analysis about the process is given finally.
机译:由于这种生物系统缺乏复杂的定量知识,因此难以对病毒感染动力学模型进行定量分析。因此,基于定性分析的方法成为复杂生物过程研究的一种替代解决方案。本文介绍了定性技术以对病毒进入过程进行建模和分析。首先提出了一个粗糙的模型,作为进一步研究的基础。通过在过程中获得更多知识,可通过插入对病毒进入过程具有交互影响的各种因素的定性说明来扩展该框架。对影响因素进行定性描述,并基于这些影响因素与病毒和细胞之间的相互作用建立定性模型。根据定性模型构造判断矩阵,并验证这些矩阵的相干性。最后对该过程进行了定性分析。

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