首页> 外国专利> Isolated molecular structure, enveloping and combining viruses, vaccine formulation, anti-corporomonoclonal, polyclonal antiserum, jelly, foam, contraceptive cream or ointment, mammal and human blood samples, kit, cell line, treatment processes or prevention of infection by a virus in subject, treatment or prevention of infection by a human infection, inhibition of infection by a virus in a blood sample, inhibition of infection by HIV in a human blood sample, decontamination of surgical or dental tools, monitoring of antibody product to molecular structure, production of an immunogen for use in a vaccine for treatment or prevention of infection by a virus, and production of an immunogen for use in a vaccine for the treatment or prevention of HIV infection, cross-linked structure, monoclonal antibody to the structure , decontamination of surgical or dental tools, pro selection process of a molecular structure for vaccine efficacy, mammal, isolated protein complex, devacin formulation, p

Isolated molecular structure, enveloping and combining viruses, vaccine formulation, anti-corporomonoclonal, polyclonal antiserum, jelly, foam, contraceptive cream or ointment, mammal and human blood samples, kit, cell line, treatment processes or prevention of infection by a virus in subject, treatment or prevention of infection by a human infection, inhibition of infection by a virus in a blood sample, inhibition of infection by HIV in a human blood sample, decontamination of surgical or dental tools, monitoring of antibody product to molecular structure, production of an immunogen for use in a vaccine for treatment or prevention of infection by a virus, and production of an immunogen for use in a vaccine for the treatment or prevention of HIV infection, cross-linked structure, monoclonal antibody to the structure , decontamination of surgical or dental tools, pro selection process of a molecular structure for vaccine efficacy, mammal, isolated protein complex, devacin formulation, p

机译:分离的分子结构,包膜和合并病毒,疫苗制剂,抗体单克隆抗体,多克隆抗血清,果冻,泡沫,避孕霜或软膏,哺乳动物和人类血液样本,试剂盒,细胞系,治疗过程或预防对象被病毒感染,治疗或预防人类感染的感染,抑制血液样本中的病毒感染,抑制人类血液样本中的HIV感染,对外科工具或牙科工具进行去污,监控抗体产物的分子结构,用于疫苗中的用于治疗或预防病毒感染的免疫原,以及用于疫苗中的用于治疗或预防HIV感染的免疫原的生产,交联结构,针对该结构的单克隆抗体,外科手术的净化或牙科工具,用于疫苗效力的分子结构的专业选择过程,哺乳动物,分离的蛋白复合物,解体素制剂,p

摘要

"ISOLATED MOLECULAR STRUCTURE, COMBINATING ENVELOPER VIRUS, VACCIN FORMULATION, ANTICORPOMONOCLONAL, POLYCLONAL ANTI-SERUM, JELLY, FOAM, CREAM OR CONTRACEPTIVE VEGETABLE, SAMPLING, DEATHING OF MAMOUSING, HUMANEOUS, HUMANEOUS, HUMANEOUS, HUMANEOUS, WOMEN IN A SUBJECT, TREATMENT OR PREVENTION OF PORHIV INFECTION IN A HUMAN, INHIBITION FROM INFECTION BY UMVIRUS IN A BLOOD SAMPLE, INHIBITION FROM HIV INFECTION IN A BLOOD SAMPLE, IN DISTRIBUTION OF HOSPITALIZATION ANTIBODY FOR THE MOLECULAR STRUCTURE, FOR THE PRODUCTION OF AN IMMUNOGENE FOR USE IN A VACCINE FOR THE TREATMENT OR FOR THE PREVENTION OF INFECTION WITH A VIRUS, AND FOR THE PRODUCTION OF A IMMUNOGENE FOR USE IN A VACCINE FOR THE TREATMENT OR THE PREVENTION OF INFECTION, HEALTHY PROTECTION, INFECTION, HEALING FOR STRUCTURE, DECONTAMINATION OF SURGICAL OR DENTAL TOOLS , PROCESS OF SELECTING A MOLECULAR STRUCTURE FOR VACCINE EFFECTIVENESS, MAMPHEROUS, ISOLATED PROTEIN COMPLEX, VACCIN FORMULATION, IMMUNIZATION PROCESSES OF AN ANIMAL FOR A VIRUS, AND PREPARATION OF A COMPLEX, PROTEIN, PURPLE PROTEIN, PROTEIN COMPLEX. , AND TREATMENT OF A HOST WITH HAVING BEEN EXPOSED TO A VIRUS, OR PREVENTION OF INFECTION OF A HOST WITH THE CITIZEN VIRUS, AND, COMPOSITION ". The invention refers to the generation of molecular structures related to fusion (FRMS) that comprise one or more determinants related to transitional mergers. Highly effective vaccines can be built which present the fusion-related determinants for the immune system that engenders unique antibodies capable of potentially neutralizing a wide variety of primary isolates, localizations from around the world and different viral-phylogenetic clades. The present invention provides FRMS formation, isolation and purification processes as well as the use of FRMS detals in a variety of compositions and processes, including for example, as vaccine immunogens, in diagnosis, and in therapy. The present invention relates to RFMS capable of generating neutralizing antibodies to viral pathogens and primary isolates of a virus. Antibodies produced for FRMS can be used to study the molecular route in the fusion direction of the virus and the host cell and to identify points of possible antibody-mediated blocking for the aquelota. The invention also relates to the use of invention antibodies in antiviral agents, blood product additives, passive contraceptive immunization additives in post-exposure treatments or in fetal immunization.
机译:“分离的分子结构,结合了包膜病毒,痘苗病毒制剂,抗小肠结肠炎,多克隆抗血清,果冻,泡沫,奶油或避孕药,采样,死皮,人,人,人,人感染人类,感染或感染人血中的病毒,感染血液样本中被细菌感染,抑制血液样本中的HIV感染,分布分子结构的医院化抗体,生产用于生产疫苗的免疫原或用于预防病毒感染,以及生产用于疫苗的免疫原,以用于治疗或预防感染,健康保护,感染,结构修复,外科手术或牙科工具的污染,选择过程疫苗效力,巨大,分离的蛋白质复合物,疫苗配方,动物免疫过程的分子结构用于病毒,并制备复合物,蛋白质,紫色蛋白质,蛋白质复合物。本发明涉及与融合有关的分子结构(FRMS)的产生,该分子结构包括以下一种或多种:可以建立高效的疫苗,为免疫系统提供与融合相关的决定因素,从而产生独特的抗体,这些抗体可以中和多种主要分离物,来自世界各地的本地化以及不同的病毒系统进化枝本发明提供了FRMS的形成,分离和纯化方法,以及FRMS方法在多种组合物和方法中的用途,包括例如作为疫苗免疫原,用于诊断和治疗。产生针对病毒病原体和病毒初次分离株的中和抗体的研究用于研究病毒与宿主细胞融合方向上的分子途径,并确定抗体介导的水通道封闭的可能点。本发明还涉及本发明的抗体在抗病毒剂,血液制品添加剂,被动避孕免疫接种添加剂在暴露后治疗或胎儿免疫中的用途。

著录项

  • 公开/公告号BR9912732A

    专利类型

  • 公开/公告日2001-11-27

    原文格式PDF

  • 申请/专利权人 THE UNIVERSITY OF MONTANA;

    申请/专利号BR19999912732

  • 发明设计人 JACK H. NUNBERG;

    申请日1999-08-03

  • 分类号C07H21/04;A61K48/00;A61K39/395;C12N1/20;

  • 国家 BR

  • 入库时间 2022-08-22 00:45:58

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