Synthesis and Evaluation of Surface Modified Folate Immobilized Silica-~(198)Au Nanocomposites

机译：表面改性叶酸固定化二氧化硅〜（198）Au纳米复合材料的合成与评价

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In this study, we described the synthesis and biological evaluation of SFS (~(198)Au) GNPs. SFSG(~(198)Au)NPs showed relatively high cellular uptake in a time dependent manner. The biodistribution of SFS(~(198)Au)GNPs showed the accumulates in tumor cells at 120 min. These results suggest that SFS(~(198)Au) GNPs has a possibilities as potential radiopharmaceuticals.

机译：在这项研究中，我们描述了SFS（〜（198）Au）GNP的合成和生物学评估。 SFSG（〜（198）Au）NPs以时间依赖性方式显示出较高的细胞摄取。 SFS（〜（198）Au）GNPs的生物分布显示在120分钟时肿瘤细胞中积累。这些结果表明，SFS（〜（198）Au）GNPs具有作为潜在放射性药物的可能性。

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来源
《8th International Conference on Isotopes 2014》|2014年|211-211|共1页
会议地点 Chicago IL(US)
作者
Jeong Hoon Park; Jun Young Lee; Min Goo Hur; Seung Dae Yang; Kook Hyun Yu; Sang Wook Kim;
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作者单位

Radiation Instrumentation Research Division, Korea Atomic Energy Research Institute, Korea;

Radiation Instrumentation Research Division, Korea Atomic Energy Research Institute, Korea ,Department of Advanced Materials Chemistry, Dongguk University-gyeongju, Korea;

Radiation Instrumentation Research Division, Korea Atomic Energy Research Institute, Korea;

Radiation Instrumentation Research Division, Korea Atomic Energy Research Institute, Korea;

Department of Chemistry, Dongguk University-Seoul, Korea;

Department of Advanced Materials Chemistry, Dongguk University-gyeongju, Korea;

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原文格式 PDF
正文语种 eng
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关键词
Au-198; folate; surfactant; Silica-gold nanoparticles; radiopharmaceutical;

机译：Au-198;叶酸表面活性剂硅金纳米粒子；放射性药物;

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2. Synthesis and evaluation of folate-immobilized Au-198@SiO2 nanocomposite materials for the diagnosis of folate-receptor-overexpressed tumor [J] . Lee Jun Young, Park Jeong Hoon, Kim Sang Wook Bulletin of the Korean Chemical Society . 2016,第2期

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4. Toll-like receptor 3 modified Au electrodes: an investigation into the interaction of TLR3 immobilized on Au surfaces with poly(I:C) [J] . Kaveh Amini, Nora W. C. Chan, Heinz-Bernhard Kraatz Analytical methods . 2014,第10期

机译：Toll样受体3修饰的Au电极：固定在Au表面的TLR3与poly（I：C）相互作用的研究
5. Synthesis and Evaluation of Surface Modified Folate Immobilized Silica-~(198)Au Nanocomposites [C] . Jeong Hoon Park, Jun Young Lee, Min Goo Hur, International Conference on Isotopes . 2014

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Synthesis and Evaluation of Surface Modified Folate Immobilized Silica-~(198)Au Nanocomposites

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