In-situ TEM nanoindentation of healthy and osteoporotic bone nanopillars

摘要

Bone is a complex,hierarchical tissue and comprises different levels of structures,from the macroscale cortical and trabecular bones down to the nanoscale bundles of mineralized collagen fibers.Studies of the microscale fracture behavior and toughening mechanism of bone have been emphasized to clarify the correlation between the hierarchical structure and the mechanical properties of bone.