摘要：
目的:分析性病门诊就诊者 HSV-1和HSV-2的感染情况.方法:用ELISA法分别检测性病门诊就诊者2911例血清中 HSV-1、Ⅱ型的IgM 和IgG 抗体.结果:2911例中,HSV-1、HSV-2,以及HSV-1和HSV-2混合感染率的95% 可信区间分别为(65.04% ~69.20%)、(0.20%~6.94%)、(14.01% ~20.61%),HSV-1感染率高于HSV-2感染率和HSV-1和HSV-2混合感染率;HSV-1和 HSV-2各年度检出率无统计学差异;男、女性 HSV-1感染率分别为70.73%、55. 07%,女性低于男性(χ2=57.267,P=0.00);而 HSV-2男、女性感染率分别为2.20%、5.07%,女性高于男性(χ2=7.805,P=0.005);男、女性 HSV-1和 HSV-2混合感染率分别为13.16%、31. 20%,女性高于男性(χ2=117.127 P=0.00).HSV-1和HSV-2既往/复发病例分别占83.68% 和19.72%,HSV-1既往感染者相对较多.HSV-1和 HSV-2的新发病例分别占1.38% 和4.65%, HSV-2型新发感染者相对较多.结论:HSV在本地区性病门诊就诊者中具有较高感染率,应进一步在性病高危人群中采取干预措施,防止HSV通过性行为在本地蔓延流行.%Objectiv:To analyse the situation of HSV-1 and HSV-2 infection in STD clinic patients.Meth-ods:Detecting IgM and IgG antibodies respectively in STD clinic patients with ELISA method.Results:With 2911 cases in STD clinic from 2013 to 2016,the infection rate and Mixed infection rate for HSV-1,HSV-2 and HSV-1with HSV-2 were 67.12%,3.37% and 17.31%.The infection rate of HSV-1 was significantly higher than HSV-2 and mixed HSV-1 and HSV-2,and no significant difference in the detection rates of HSV-1 and HSV-2 in each year.For HSV-1 infection rates with Male and female were 70.73% and 55.07%,respectively,and women were lower than men(χ2=57.267,P=0.00).For HSV-2 infection rates with male and female were 2.20% and 5.07%,respective-ly,and women were higher than men(χ2=7.805,P=0.005).Male and female mixed infection rates of HSV-2 and HSV-1 were 13.16% and 31.20% respectively,which were higher in female than in male(χ2=117.127,P=0.00). HSV-1 and HSV-2 were 83.68% and 19.72% in the previous /recurrent cases,and HSV-1 was relatively high in the previous cases.Conclusion:HSV in the local STD clinic patients with a high rate of infection,should be further in high-risk groups of sexually transmitted diseases to take interventions to prevent the spread of HSV through sexu-al behavior in the local epidemic.
