摘要：
目的 通过多模态成像来发现moyamoya病症状,脑血管病变和侧支循环之间的相关性.方法 本文回顾性分析了2010年~2016年我院医院记录和诊断为moyamoya病的22例患者,根据CT和MRI分为颅内出血组和脑梗死组.根据患者的CT或MRI表现进行分期和评分.使用DSA结合CTA或MRA分类侧支循环.对临床症状,颅内损伤,年龄和脑血管事件进行相关性分析,确认组间无显著性差异.结果 颅内出血组和梗死组年龄,性别无显著性差异,蛛网膜下腔&脑室组出血发病率除外( P =0.008).出血组与蛛网膜下腔&脑室组,梗塞组和蛛网膜下腔&脑室组,皮质病变部位和梗塞组之间的Spearman相关系数分别为0.516( P =0.014), -0.690( P =0.000),0.574( P =0.005).年龄和意识障碍,意识障碍和头痛,癫痫发作和智力障碍之间的Spearman相关系数分别为0.428( P =0.047),-0.542( P =0.009),0.690( P =0.000).moyamoya分级和肌肉无力,基底节区病灶和肌肉无力之间的 Spearman相关系数分别为0.506( P =0.016),0.436( P =0.043).第二条侧支旁路和性别之间的Spearman相关系数为0.463( P =0.030).第三条侧支旁路与头痛之间的 Pearson 相关系数为0.510( P =0.015).分期和积分的 Pearson 相关系数为0.616( P =0.002).结论 结果表明,临床症状与moyamoya病的病变面积和分期相关.临床症状和侧支循环的类别相关.这些都可以用以评估临床预后和预防并发症的发生.%Objective To determine the correlations between the moyamoya disease symptoms and the cerebrovascular lesions and collateral circulation by multi-modality imaging. Methods This study retrospectively analyzed 22 patients who had been re-corded and diagnosed with moyamoya disease in our hospital from 2010 to 2016. All patients were categorized into the intracranial hemorrhagic group or cerebral infarction group based on CT and MRI performance. Researchers made the classification and score according to the patients'CT or MRI performance. This study used DSA combined with CTA or MRA to classify collateral circula-tion. The study analyzed the clinical symptoms,intracranial lesions,age,and cerebrovascular events by correlation analysis after confirming no significant difference in the grouping. Results The intracranial hemorrhage group and infarction group in age,gen-der had no significant difference,except for the incidence of subarachnoid&ventricle group( P =0.008). The Spearman correla-tion coefficients between the hemorrhage group and subarachnoid&ventricle lesions group,the infraction group and subarachnoid& ventricle lesions group,lobar lesion location and infraction group were 0.516( P =0.014),-0.690( P =0.000),0.574( P=0.005),respectively. The Spearman correlation coefficient between age and consciousness disturbance,consciousness disturb-ance and headache,seizure and intellectual disturbance were 0.428( P =0.047),-0.542( P =0.009),0.690( P =0.000), respectively. The Spearman correlation coefficient between the stage classification and Muscle weakness, the basal ganglia and Muscle weakness were 0.506( P =0.016),0.436( P =0.043),respectively. The Spearman correlation coefficient between the second pathway and gender was 0.463( P =0.030). The pearson correlation coefficient between the third pathway and headache was 0.510( P =0.015). The pearson correlation coefficient of stage classification and scoring was 0.616( P =0.002). Conclu-sion The results suggested that the clinical symptom was associated with the lesion area and the stage classification in moyamoya disease. The clinical symptoms and collateral circulation type were related. These were worthy in the assessment of the clinical prognosis and prevention of complications.
