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冲击伤

冲击伤的相关文献在1985年到2022年内共计299篇,主要集中在外科学、特种医学、眼科学 等领域,其中期刊论文252篇、会议论文7篇、专利文献49772篇;相关期刊102种,包括中国生物医学工程学报、中国急救医学、创伤外科杂志等; 相关会议6种,包括2012浙江省烧伤外科学学术年会、中华医学会航海医学分会第九次学术会议暨全军第九届航海医学专业委员会第一次学术会议、第十三届全国激波与激波管学术会议等;冲击伤的相关文献由637位作者贡献,包括王正国、杨志焕、李晓炎等。

冲击伤—发文量

期刊论文>

论文:252 占比:0.50%

会议论文>

论文:7 占比:0.01%

专利文献>

论文:49772 占比:99.48%

总计:50031篇

冲击伤—发文趋势图

冲击伤

-研究学者

  • 王正国
  • 杨志焕
  • 李晓炎
  • 刘大维
  • 朱佩芳
  • 周继红
  • 李兵仓
  • 蒋建新
  • 冷华光
  • 侯立军
  • 期刊论文
  • 会议论文
  • 专利文献

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    • 陈雪梅; 崔欢欢; 郭丽琼; 樊毫军; 刘子泉
    • 摘要: 高原肺冲击伤是发生于高原地区的冲击伤,与平原冲击伤不相同,其伤情受冲击波致伤参数和高原低压缺氧环境的综合影响。本文就高原肺冲击伤的特点、致伤机制及救治进行综述。
    • 李森; 王海燕; 龙在云; 刘媛; 高洁; 杜娟; 蒋建新; 王正国; 杨策
    • 摘要: 现代高技术战争中,在以非接触和精准打击为特点的作战样式推动下,战场环境必将更加复杂.中国国土幅员辽阔,边境线漫长,面对我国国家安全面临的风险挑战,高原、海岛、沙漠、丛林等地域因其严峻的气候和自然条件(低气压、低氧、水域、高热、高湿、极寒、密闭空间),战伤种类、伤情、救治、康复较普通环境战伤更为棘手,是决定战争胜负的重要制约因素.鉴于高爆武器是未来战争的主要杀伤兵器,爆炸冲击伤是其主要伤类,且其伤情重、伤势复杂,早期死亡率极高,开展特殊环境冲击伤及其防治研究,对于减少特殊环境作战人员伤亡,有效控制并发症发生,提升临床救治效能具有重要军事医学价值.
    • 巨圆圆; 阮狄克; 徐成; 胡明; 刘立洋; 陈佳海; 王静; 李军; 龙仁荣
    • 摘要: 目的 分析空气冲击波作用下兔肺部载荷特性,为冲击波毁伤评估及其防护救治提供参考.方法 建立兔胸部二维平面模型,利用ANSYS Autodyn有限元分析软件模拟90 g TNT装药爆炸,0.5 m爆炸距离处兔胸部的动态响应.结果 在冲击波与兔胸部接触的局部区域,肺部压力首先由壁面压力波经肌肉、骨骼透射进入肺部产生;肺部其他区域的压力首先由骨骼中传播的应力波透射进入肺部产生.结论 空气冲击波作用下,兔肺部载荷由壁面压力波的直接作用和骨骼变形运动、骨骼-肺界面反射及空穴效应的间接作用共同决定.%Objective The loading characteristics of air shock wave on the lung of rabbit are analyzed, which may provide reference for the evaluation of blast injury and its prevention and treatment. Methods A two-dimensional plane model for the lung of rabbit is established, and its dynamic response to 90 g TNT explosive with a distance of 0.5 m is simulated by ANSYS Autodyn finite element analysis software. Results In the local area where shock wave directly interacts with thorax, pulmonary pressure is covered by the stress wave which is transmitted from the wall-surface compression wave through muscle and bone. The pulmonary pressure in other area is covered by the stress wave which is transmitted from that in the bone. Conclusion The loading characteristics of air shock wave on the lung of rabbit include the direct action of the wall-surface compression wave and the indirect action of the bone deformation, and the reflection from the interface of bone and lung as well as the cavitation effect.
    • 谢锋; 柴家科; 胡泉; 郁永辉; 翟弘峰; 侴海燕; 康深松
    • 摘要: 目的 探讨烧冲复合伤大鼠心肌损伤及钙蛋白酶的变化规律.方法 128只雄性SD大鼠按随机数字表法分为对照组、烧伤组、冲击伤组、复合伤组各32只.对照组:37°C温水中12 s,烧伤组:94°C的沸水中12s,冲击伤组:5 g黑索今距离大鼠左胸壁75 cm爆炸,复合伤组:5g黑索今距离大鼠左胸壁75 cm爆炸后94°C的沸水中12s.伤后6、24、48、72 h4个观察点,采集腹主动脉血和心肌标本;测定左心室射血分数(EF)、左心室短轴缩短指数(FS);心肌组织HE染色;血清肌钙蛋白Ⅰ(CTnI)、肌酸激酶同工酶(CK-MB)检测;Tunel染色检测心肌组织细胞凋亡;实时荧光定量聚合酶链反应(RT-PCR)及Western印迹法分析心肌中钙蛋白酶mRNA及蛋白表达变化;荧光光度法检测钙蛋白酶活性.结果 复合伤组伤情变化明显,心肌间质水肿明显,可见大面积心肌细胞变性及崩解,中性粒细胞浸润数量增多.伤后24h烧伤组、冲击伤组、复合伤组心功能下降,EF和FS均显著低于对照组(均P<0.05).复合伤组伤后72 h时FS和EF,48 h时FS均显著低于烧伤组、冲击伤组(均P<0.05);复合伤组cTnI上升,各个时间点均显著高于对照组,48 h时均显著高于烧伤组与冲击伤组(均P<0.05);复合伤组CK-MB伤后逐渐升高,24h时降低,48 h时再升高且均显著高于对照组与烧伤组(均P <0.05).伤后烧伤组、冲击伤组、复合伤组心肌凋亡指数均显著高于对照组(均P<0.05),烧伤组24、48 h时分别为(25.3±4.0)、(28.8±5.3),均显著低于同时间点复合伤组的(43.3±9.4)、(53.3±10.4),烧伤组72 h时为(31.9±6.7),显著高于冲击伤组的(17.3±6.3)(均P<0.05).各时间点复合伤组心肌组织中钙蛋白酶mRNA和蛋白相对表达量均显著高于对照组(均P<0.05).复合伤组心肌钙蛋白酶活性伤后24h达到高峰,后逐渐下降,各时间点均显著高于对照组(均P<0.05).结论 烧冲复合伤后大鼠出现心肌损伤,钙蛋白酶蛋白表达升高、活性增强.%Objective To study myocardial damage and rules of calpain change in rats with burnblast combined injury.Methods One hundred and twenty-eight male SD rats were randomly divided into control group,bum group,blast group,bum-blast group,with 32 rats in each group.Control group:37 degrees' warm water for 12 s;Burn group:94 degrees' boiling water for 12 s;Blast group:5 g cyclonite explode in 75 cm distance from left chest wall of rat;Burn-blast group:burn group and blast group combined modeling method.At 6,24,48,72 h observation points after injury,abdominal aorta blood samples and myocardial specimen were collected.Left ventricular ejection fraction (EF),left ventricular fractional shortening index (FS) were measured through color Doppler ultrasound instrument;Myocardial tissue was stained with hematoxylin-eosin (HE);serum cardiac troponin Ⅰ (CTnI) and creatine kinase isoenzyme (CKMB) were detected;detection of cell apoptosis in myocardial tissue was performed by terminal deoxynuclcotidyl transferase-mediated dUTP notch labehng technique (Tunel).Expression levels of calpain mRNA levd and protein were detected with Real-time fluorescent quantitative polymerase chain reaction (RT-PCR) and Western imprinting method analysis;calpain activity was detected by fluorescence spectrophotometry.Results The injury of burn-blast combined injured rats was obvious,including myocardial interstitial edema,large area of myocardial cell degeneration and disintegration and the number of neutrophil infiltration increased.Cardiac function decreased 24 h after injury in burn group,blast group,burn-blast group;both EF and FS were significant lower than those of control group (all P < 0.05).FS at 48,72 h and EF at 72 h in burn-blast group were significantly lower than those of burn group,blast group at the same time points (all P < 0.05);the level of cTnI in burn-blast group rose and was higher than control group at all time points,higher than the burn group,blast group at 48 h (all P < 0.05).CK-MB in burn-blast group rats increased after injury,lowered at 24 h and rose again at 48 h.The level was significantly higher than control group and burn group (both P < 0.05).Comparing to control group,myocardial apoptosis index in burn group,blast group and burn-blast group were significantly increased (all P <0.05).Those of burn group (25.3 ± 4.0) at 24 h and (28.8 ± 5.3) at 48 h were significantly lowered than burnblast group (43.3 ±9.4),(53.3 ± 10.4) at same time points,and burn group (31.9 ±6.7) at 72 h was signicantly higher than blast group (17.3 ± 6.3) (all P < 0.05).Compared to control group,Calpain mRNA and protein expression in myocardial tissue were significantly increased in burn-blast group at all time points (all P <0.05).Calpain activity reached the peak at 24 h after injury,then gradually declined,and was significantly higher than control group (all P < 0.05).Conclusion Calpain expression and activity increase in burn-blast combined injured rats which leads to myocardial damage.
    • 赵辉; 朱峰
    • 摘要: 随着现代各种爆炸性武器尤其是各种简易爆炸装置(improvised explosive devices,IEDs)的出现,冲击伤已成为一种常见伤类.原发性颅脑冲击伤系冲击波直接作用人体导致的颅脑损伤,其危害正受到广泛关注.为研究原发性颅脑冲击伤的病因学和病理特点,以提高颅脑冲击伤的防护和救治水平,迄今已通过多学科融合、多种研究手段相结合来开展原发性颅脑冲击伤研究.本文对冲击波物理特性、冲击伤实验方法、颅脑冲击伤力学机制和阈值等原发性颅脑冲击伤的生物力学机制内容进行简要介绍,以期引起更多关注.
    • 杨策; 蒋建新; 杜娟; 王海燕; 高洁; 庄茁; 柳占立; 王正国
    • 摘要: 爆炸事故发生后,肺脏作为最易受累的靶器官之一,是临床爆炸冲击伤诊治的重点。既往对肺脏冲击伤诊治措施主要依据伤员症状、体征和影像学、血气分析数据,在改善通气、限制性补液、预防空气栓塞、感染并发症及必要的外科对症治疗。然而,随着社会的发展,爆炸物种类、形式、当量、理化性质以及爆炸场的复杂空间分布更趋多样,肺爆炸冲击伤伤情特点、诊治措施以及预后转归等呈现更多的复杂性和非线性特点。为此,基于预防性、预测性、个体化和参与性的“4P”医学模式,从转化医学视角辨析肺爆炸冲击伤的伤情发生和变迁规律,探究肺爆炸冲击伤理论成果在肺爆炸冲击伤精准治疗中的可行性,尝试从既往以定性为主的常规诊治转化至以量化评估的个体化精准诊治,旨在为探索肺爆炸冲击伤精准救治范式提供有益的借鉴和启示。%In the explosive accidents, lungs are the most easily injured organs owing to the blast wave.The pulmonary blast injury (PBI) constitutes the key aspect in the diagnosis and therapy of explosive blast injury.Presently,the diagnosis of PBI mainly depends on the symptom,signs,blood gas analysis and imaging of the wounded. The clinical treatment focuses on the ventilation improvement, restrictive fluid infusion,prevention of air embolism,treatment of possible infectious implications as well as necessary surgical procedures. However, with the social development, the categories, patterns, equivalent weight, physico⁃chemical property of explosive substance and more complicated spatial distribution of explosive sites,the state of PBI, measures of its diagnosis and therapy and prognostic outcome demonstrated the characteristics of complexity and nonlinearity.Hence,based on the 4P ( preventive,predictive,personalized and participatory, 4P) medicine model,it is of great necessity to discriminate the regularity of happening and transformation of PBI from the view of translational medicine and to investigate the probability of precision treatment of PBI by given its previous theoretical results.It may propel the transformation of patterns of its diagnosis and therapy from routine experienced qualitative treatment to personalized quantative precision treatment. The aim of this study tries to supply a new paradigm for the precision diagnosis and therapy of PBI.
    • 高洁; 王永堂; 刘媛; 王莉; 伍亚民; 赖西南; 蒋建新; 杨策
    • 摘要: The explosive accidents happened frequently. Patients with disabling brain injury constitute the main population which is paid little attention. Based on the current researches about mild traumatic brain injury,post traumatic stress disorder ( PTSD) and chronic traumatic encephalopathy,the blast mechanism, pathophysiology, diagnosis, medical treatment, difficulties and the future progress are systematically reviewed. The early diagnosis, early prevention and first⁃aid psychological intervention are emphasized for the brain health of the population suffering from exposure of explosive blast injury.%爆炸事件越来越频繁,以无临床指征和影像学表现为特点的失能性脑损伤患者是主要群体,但一直缺乏关注。笔者基于轻度创伤性脑损伤、创伤后应激障碍、慢性创伤性脑病,系统回顾了国内外关于失能性脑损伤的伤情特点、诊断、措施以及特殊环境下爆炸伤的救治难点和最新诊治前景。强调早诊治、早防护以及及时地心理干预,为诊治和防护爆炸冲击伤后亲历者的脑损伤提供有益启示。
    • 杨策; 蒋建新; 杜娟; 王海燕; 高洁; 柳占立; 庄茁; 王正国
    • 摘要: Objectives To investigate the epidemiological characteristic of explosion accidents as well as the possible measures for their diagnosis and treatment.Methods We retrospectively investigated the accidents reasons, injury regularity and casualty characteristic of 174 explosion accidents in China from January 1, 2000 to October 1, 2015. The integrated strategy of explosion prevention, injury relief and psychosomatic rehabilitation were also been analyzed from the view of prevention,diagnosis and treatment of explosive blast injury. Results The explosion accidents happened in 30 provinces, municipalities and autonomous regions in China. The explosive elements were complicated and diversified, mainly including chemicals,dust,cell phones,burning air,improvised explosive devices,gas,fireworks,petroleum,boilers and other rare explosive goods. Among them, explosions of chemicals, dust and cell phones constituted the first three major reasons.In these 174 accidents,the total number of casualty reached 7062.The numbers of injured and died were 4313 and 2749 respectively. The average numbers of casualty per accident were 24. 79 (injured),15.80 (died),40.59 (casualty).The numbers of accidents located the first three major types were 33 (79%) for chemical,21 (78%) for dust and 20 (91%) for burning air in injured people exposed to explosion accidents.The casualty of chemical (2 714/7 062),dust (1 268/7 062) and gas (1 215/7 062) explosions located the first top three types. Correspondingly,the numbers of casualty per accident were 67.00, 46.96 and 93.46 respectively,while the casualty ratios were 88%,81% and 100%.Conclusions Given the epidemiological characteristics of explosive blast injury in China,we need to form the expert consensus for the diagnosis and treatment of explosive blast injury in view of an individualized idea. The efficient remedy flowsheet and emergency team via multiple subjects′integration are also in great need.Concurrently,the new equipment and measures of diagnosis as well as treatment concerning the individualized remedy should also be considered.%目的:分析国内近十五年爆炸事故冲击伤流行病学特点及其变迁规律。方法回顾性调查国内2000年1月1日至2015年10月1日近15年174起爆炸事件的发生原因、致伤规律以及伤亡特点,探究基于爆炸冲击伤防、诊、治的防御爆炸、减轻损伤、康复身心的一体化策略。结果爆炸事件覆盖中国30个省、市、自治区。爆炸物成份复杂,类别多样,主要有化学品、粉尘、手机、燃气、临时爆炸装置、瓦斯、烟花爆竹、油料、锅炉以及其他少见爆炸物等,其中化学品、粉尘和手机位居爆炸原因的前3位。174起爆炸事件中,累积伤亡人数7062人,受伤人数4313人,死亡人数2749人。平均每起爆炸事件伤亡数为:受伤数24.79人/起,死亡数15.80人/起,伤亡数40.59人/起。化学品(33起,79%)、粉尘(21起,78%)和燃气(20起,91%)爆炸位居暴露人员发生受伤事故数的前3位。化学品、粉尘和瓦斯爆炸伤亡人数位居前3位(2714人/7062人,1268人/7062人和1215人/7062人),对应平均每起伤亡人数分别为67.00人、46.96人和93.46人,对应伤亡率分别为88%,81%和100%。结论针对国内爆炸冲击伤的流行病学特点,需要针对新情况按照个体化诊治思路,形成爆炸冲击伤专家共识,建立符合国情的爆炸冲击伤救治流程,多学科整合形成应急救治小组,并基于个体化救治需求拓展诊治新设备和新措施。
    • 王正国
    • 摘要: Blast injury usually occurs in human bodies exposed to blast wave (shock wave).War conflict and accidents account for the pathogenesis of blast injury.Since entering the 21th century,the Chinese achievement in social progress and economical development has grasped the world′s eyesight.Nevertheless,in the field of social safety especially facing the aggravation of regional contradiction and local conflict in the world,the explosion accidents have showed the tendency of gradual increase and diversification.Furthermore, these non⁃martial blast injuries have manifested some new characteristics in traumatic condition as well as outcome.Thus,we need to deeply understand the historical transition of explosive blast injury,clearly know its principle of precision diagnosis and treatment. It is valuable to break through the theoretical and technological bottleneck for research in blast injury.Moreover,it is of great clinical value and social significance.%冲击伤是在冲击波作用下,机体所发生的各种损伤。战争冲突、意外伤害是冲击伤发生的主要原因。进入二十一世纪以来,中国社会进步和经济发展为世界瞩目。然而,在社会安全领域,特别是在全球区域性矛盾和局部冲突加剧的背景下,爆炸事故渐增且呈多样化趋势,并在伤情和转归方面表现出与战时冲击伤不尽相同的新特点。为此,深入了解人类对爆炸冲击伤认识的历史变迁,洞悉其精准诊治原则,对于突破冲击伤研究的理论和技术瓶颈,切实提升我国冲击伤的预防、诊断和治疗水平,具有重要的临床价值和深远的社会意义。
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