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兔眼

兔眼的相关文献在1975年到2022年内共计167篇,主要集中在眼科学、皮肤病学与性病学、药学 等领域,其中期刊论文145篇、专利文献22篇;相关期刊88种,包括中国保健、中国麻风皮肤病杂志、中国眼耳鼻喉科杂志等; 兔眼的相关文献由408位作者贡献,包括廖优江、文光琴、聂飞等。

兔眼—发文量

期刊论文>

论文:145 占比:86.83%

专利文献>

论文:22 占比:13.17%

总计:167篇

兔眼—发文趋势图

兔眼

-研究学者

  • 廖优江
  • 文光琴
  • 聂飞
  • 任金萍
  • 冯艳玲
  • 姚汉武
  • 孔丽
  • 胡俊喜
  • 钱坚革
  • 陈胜天
  • 期刊论文
  • 专利文献

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    • 任珊珊
    • 摘要: 很多人在眼疲劳时会用热毛巾捂眼或者按摩眼部穴位,缓解效果十分明显。近年来,有热疗作用的眼部按摩仪因操作方便、省力,颇受职场人士欢迎。然而,广州的市民许女士(化名)没想到,一次眼部按摩竟让她的两只眼睛变成红通通的“兔眼”。中山大学附属第六医院眼科主任夏朝霞指出,护眼“高科技”并非人人适用,使用不当的话,养眼不成反伤眼。
    • 周欣; 于东毅; 何大伟
    • 摘要: 目的:研 究 准 分 子 激 光 治 疗 性 角 膜 切 削 术(phototherapeutic keratectomy,PTK)对兔眼细菌性角膜溃疡愈合的影响,并探讨该方法用于临床上治疗细菌性角膜病变的可能性.方法:24只新西兰大耳兔48眼接种金黄色葡萄球菌,成功制作细菌性角膜溃疡模型.接种细菌后1~2d溃疡明显形成,予以左氧氟沙星滴眼液滴眼.术前行双眼前节裂隙灯检查,双眼光学相干断层扫描(optical coherence tomography,OCT)检查并测量角膜溃疡中央深度.接种3d后所有实验兔右眼行PTK手术,左眼不予以处理作为对照眼.术后3、7d再行裂隙灯检查,并行OCT检查测量角膜溃疡中央厚度.术后7d处死实验兔,摘除双眼眼球取角膜组织行病理切片观察.结果:经裂隙灯观察,随时间推移两组兔眼角膜溃疡均有愈合倾向,表现为溃疡面积缩小和表面变平坦光滑.观察组术前测量角膜溃疡深度与对照组比较,差异无统计学意义(t=0.706,P=0.484).观察组术后3、7d角膜溃疡厚度与对照眼比较,差异有统计学意义(P<0.05).结论:PTK能有效治疗兔眼金黄色葡萄球菌性角膜溃疡,促进溃疡创面愈合,这可能为PTK应用于临床治疗患者细菌性角膜病变提供实验依据.%AIM: To study the effect of phototherapeutic keratectomy (PTK) on rabbit bacterial corneal ulcer model and explore the clinical potential of this method. METHODS:Totally 48 eyes from all the 24 New Zealand rabbits were inoculated with Staphylococcus aureus and bacterial corneal ulcer model was established successfully. At 1d after inoculation,48 eyes were given levofloxacin eye drops when corneal ulcer was confirmed. Then slit lamp inspection and optical coherence tomography ( OCT) were performed to measure the central corneal ulcer depth. All the rabbits right eyes were treated with PTK, as an observation group,left eyes were not treated as a control group. The eye section were observed by slit lamp and central thickness of corneal ulcer was measured by OCT at 3 and 7d after this operation. Rabbits were sacrificed and the cornea was removed for pathological section 7d later. RESULTS: The corneal ulcers in both groups had a tendency to heal, showing a decrease in ulcer area and smoothness of the surface. There was no significant difference in the depth of corneal ulcer between the observation group and the control group before PTK (t=0.706,P=0.484). The difference between the two groups of eyes at 3 and 7d after PTK was obviously (P<0.05). CONCLUSION: PTK can effectively cure rabbit Staphylococcus aureus corneal ulcer and promote ulcer wound healing,which may be used for clinical treatment of patients with bacterial corneal lesions.
    • 郭辉; 田紫煜; 王影; 刘绍燕; 李淑敏; 安荣荣; 苑文佳; 孟言; 白鹏
    • 摘要: 目的 制备兔眼前部缺血性视神经病变动物模型,为前部缺血性视神经病变相关研究提供可参考的模型制备方法.方法 新西兰大耳白兔12只,均以右眼为实验眼,左眼为空白对照,本研究以孟加拉玫瑰红(90%纯度)为光敏剂,选用532 nm绿光、功率75 mW、光斑直径为1000 μm的激光制备兔眼前部缺血性视神经病变(AION)模型.通过眼底镜及荧光素眼底血管造影检查(FFA)观察视盘情况;通过苏木精-伊红染色法(HE)观察了兔眼组织病理变化.结果 前部缺血性视神经病变兔眼的表现:(1)视盘水肿;(2)FFA检查示造影早期可见家兔视盘上方低荧光,中、晚期高荧光;(3)HE染色病理可见视网膜神经节细胞层出现增生现象,排列十分紊乱,内核层明显变薄,细胞数目明显减少.结论 孟加拉玫瑰红诱导下激光照射法可以作为兔眼AION模型制备方法.
    • 陈姣; 邓芸; 赵雁之; 元芳秀; 刘维锋
    • 摘要: 目的 研究全视网膜激光光凝治疗对贝伐单抗在兔眼玻璃体、 视网膜脉络膜中的药物代谢动力学的影响.方法灰兔18只,左眼行全视网膜激光光凝术(激光组),右眼设为对照组(未激光组);2周后在其双眼玻璃体腔分别注射1.25mg(O.05m1)贝伐单抗,于药物注射1h、ld、2d、4d、14d、30d后收集玻璃体、视网膜脉络膜样本,采用酶联免疫吸附试验(ELISA)检测样本中贝伐单抗浓度;采用t检验法比较不同时间点激光组和对照组中贝伐单抗的浓度差异;根据梯形面积法计算30d内贝伐单抗在兔眼的药-时曲线下面积(AUC30d),评价其暴露量.结果药物注射1h后,玻璃体贝伐单抗平均浓度在激光组、对照组分别是(43.58±6.67)μg/ml、(39.15±5.21)μg/ml;视网膜脉络膜内平均浓度分别是(27.72±5.33)μg/ml、(25.06±6.69)μg/ml;1d后,激光组、对照组玻璃体平均浓度分别是(32.82±2.05)μg/ml、(37.26±3.04)μg/ml;视网膜脉络膜平均浓度分别是(27.13±1.16)μg/ml、(25.28±6.79)μg/ml;2个时间点贝伐单抗浓度在对照组和激光组比较差异无统计学意义(均P>0.05);2d后对照组、激光组玻璃体贝伐单抗浓度分别为别降低为(37.02±2.02)μg/ml、(30.37±1.80)μg/ml,两者比较差异有统计学意义(P=4.24,t=0.01);其余各时间点两组样本比较差异均无统计学意义(P>0.05).药物注射30d内,贝伐单抗在对照组、激光组兔眼玻璃体中的暴露量分别为AUC30d为919.825μg/ml·d,732.285μg/ml·d,差异有统计学意义(P=0.04).视网膜脉络膜中的暴露量AUC30d分别是729.115μg/ml·d、724.505μg/ml·d,经比较差异无统计学(P=0.58).结论全视网膜激光光凝术在一定程度上会降低贝伐单抗在兔眼玻璃体内的浓度和暴露量.
    • 刘雯婷; 熊毅彤; 张宇燕
    • 摘要: Objective To evaluate the influence of a selective Rho-associated protein kinase inhibitor (fasudil hydrochloride) on outflow facility in enucleated porcine,rabbit and bovine eyes.Methods At the constant perfusion pressure of 15 mm-Hg (1 kPa =7.5 mmHg),the baseline coefficient of outflow facility (C0) of the isolated porcine,rabbit and bovine eyes was recorded respectively.The enucleated porcine eyes were divided into two groups randomly (n =6),and they were control group and experimental group.The same grouping method was also used-C0 the ribbit and bovine eyes.The control group was subjected to GPBS perfusion,while the experimental group was treated with 100 μmol · L-1 fasudil solution,followed by recording the experimental coefficient of outflow facility (C1),as well as calculating ΔC (ΔC =C1-C0) and ΔC% (ΔC% =ΔC/C0).Finally,the paired t test and one-way analysis of variance were performed using SPSS 17.0.Results As for porcine eyes,the ΔC% of the control group was (17.83 ± 3.84) % while the experimental group was (44.00 ± 6.44) %;as for rabbit eyes,the ΔC% of the control group was (15.50 ± 2.93) %,while the experimental group was (31.67 ±6.54)%;as for bovine eyes,the ΔC% of the control group was (11.67 ± 1.17)%,while the experimental group was (37.17 ± 4.48)%.The ΔC% in the experimental group was significantly increased when compared with the control group in three animals,with significant difference (all P < 0.05).There was no statistical difference in ΔC% of three experimental groups among different kinds of animals (all P < 0.05).Conclusion Fasudil can improve outflow facility in enucleated eyes of animals,and it can redistribute aqueous humor drainage to a wider area through directly regulating the cytoskeleton of cells and matrix,resulting in increased coefficient of outflow facility.%目的 评价选择性Rho激酶抑制剂盐酸法舒地尔对离体猪眼、兔眼及牛眼的房水流畅系数的影响.方法 在15 mm-Hg(1 kPa=7.5 mmHg)恒压灌注条件下,先记录离体猪眼、兔眼及牛眼的基线房水流畅系数(C0),然后随机将眼球分为对照组及实验组,每组6只,对照组使用GPBS、实验组使用100 μmol·L-1盐酸法舒地尔溶液继续灌注,记录实验房水流畅系数(C1),并计算房水流畅系数增加值ΔC(ΔC=C1-C0)及房水流畅系数增加百分比ΔC%(ΔC%=ΔC/C0),利用SPSS 17.0进行配对t检验及单因素方差分析.结果 猪眼对照组、实验组的ΔC%分别为(17.83±3.84)%、(44.00±6.44)%;牛眼对照组、实验组的ΔC%分别为(11.67±1.17)%、(37.17±4.84)%;兔眼对照组、实验组的ΔC%分别为(15.50±2.93)%、(31.67±6.54)%,三种动物眼的实验组ΔC%较对照组均明显增加,差异均有统计学意义(均为P<0.05).三种不同动物离体眼实验组的ΔC%之间差异无统计学意义(F=1.064,P=0.370).结论 盐酸法舒地尔可以增加不同种类离体动物眼房水流畅系数,其作用可能是通过调节小梁房水流出道的细胞及基质骨架结构,重新分布房水引流到一个更广泛的区域而发挥增加房水流畅系数的作用.
    • 胡建省; 杨瀛; 龙青文; 程曦
    • 摘要: AIM:To study the effect of different surgeries for vision and postoperative complications in leprosy patients with lagophthalmos.METHODS:A retrospective analysis.Totally 68 leprosy patients (97 eyes) with lagophthalmos were selected who treated with different surgeries during May 2007 to September 2015 in our sanatorium.The surgeries included nylon thread correction surgery, tarsorrhaphy, temporalis transposition surgery.We observed and compared the best corrected visual acuity(BCVA) and the rate of postoperative complications, such as epiphora, lacrimal duct injury, hard to open eyes, infection at the inner and lateral canthus and scar formation of lacrimal apparatus.RESULTS:The effect on BCVA of patients treated with nylon thread correction surgery and tarsorrhaphy:the preoperative and postoperative BCVA was significantly different of the two groups (Z=-4.193,-4.213;P0.05).The postoperative complications:(1) epiphora:there was 91% in patients underwent nylon thread correction surgery, 89% in patients underwent tarsorrhaphy, 59% in patients underwent temporalis transposition surgery, the difference was statistically significant (χ2=12.198, P0.05).术后并发症:(1)溢泪:尼龙线矫治术占91%,眼睑缝合占89%,颞肌移位术占59%,三者比较差异具有统计学意义(χ2=12.198,P<0.05);(2)泪器损伤:尼龙线矫治术占66%,眼睑缝合术占95%,颞肌移位占41%,三者比较差异具有统计学意义(χ2=22.415,P<0.05);(3)睁眼困难:尼龙线矫治术占56%,眼睑缝合术占55%,颞肌移位术占22%,三者比较差异具有统计学意义(χ2=8.795,P<0.05);(4)术后感染:尼龙线术占84%,眼睑缝合术占3%,颞肌移位占11%,三者比较差异具有统计学意义(χ2=60.858,P<0.05).结论:麻风性兔眼手术矫治虽有一定的临床效果,尤其是颞肌移位术后患者能主动闭眼,其视力、视觉质量无显著变化.提示该手术可预防角膜的暴露性损害.但手术造成的医源性损伤与其他组间患者的视觉质量下降和眼组织损害(溢泪、泪道损伤、内外眦部感染、泪器组织瘢痕化等)应引起足够的重视.
    • 张冰洁; 张远平; 马林昆; 周伟; 赵学英; 孙恒; 王丽超; 郭晓艳
    • 摘要: 目的 探索更好的碱烧伤兔眼的人工角膜移植手术方式.方法 使用2种不同的手术方式将改进的人工角膜植入2组碱烧伤兔眼(A组和B组),A组行人工角膜植入术,B组行人工角膜植入联合虹膜切除和前节玻切术,观察人工角膜术后结果.结果 A组平均在位时间为273.58 d,B组平均在位时间为374.42 d;A组手术后7眼出现高眼压的情况,而B组仅有1眼眼压增高.2组在位时间及高眼压的比较,差异有统计学意义(P<0.05).结论 联合虹膜切除和前节玻切的人工角膜植入手术操作方式是一种更好的的手术方式.%Objective To search a better operation method for the keratoprosthesis transplantation in alkali-burned rabbit eyes.Methods The improved keratoprostheses were implanted into 2 groups (A and B) of alkali-burned rabbit eyes by using 2 different operation methods:in group A,the keratoprostheses were implanted singlely;in group B,the keratoprostheses were implanted combined with iridectomy and anterior vitrectomy.We evaluated the postoperative outcomes.Results The average retention time in group A was 273.58 days;In group B was 374.42 days.7 eyes in group A had increased intraocular pressure postoperatively,while Only 1 eyes had increased intraocular pressure in group B.The difference between the two groups was statistically significant in the retention time and increased intraocular pressure.Conclusion The iridectomy-combined operation method (group B) is a better keratoprosthesis implantation method.
    • 唐凤雄
    • 摘要: 光棍民国二十年孟春时节的一个白昼,桑槐坪光棍唐天才在山中砍柴禾,于青翠草丛中倏地掠出一只雪似的白兔,径直从唐天才胯下钻过,唐天才愣过神来,却见白兔支立在三丈开外,似笑非笑的一双兔眼亮亮地煽动他的欲望,他持刀便撒腿追赶,白兔便向西不急不慢地跑,总甩开他三丈远的距离。如此持续了数里,白兔在一山洞不见了。唐天才累了一身饱汗,不甘就此罢手,猫着腰就钻进了窄小的山洞。一女子蜷缩在阴湿的山洞旮旯里,唐天才以为是逃荒的叫化婆,一推没有动静,手一探,尚有微弱鼻息。
    • 摘要: 小时候我们都喜欢唱"小白兔,白又白,两只耳朵竖起来……"的儿歌,那你注意到小白兔的眼睛是红色的了吗?一般来说,兔子眼睛的颜色与身体皮毛的颜色是一致的。换句话说,兔子的身体内部含有哪种色素,毛和眼睛便呈什么颜色。如灰兔子的眼睛是灰色的,黑兔子的眼睛是黑色的。这样说来,小白兔的眼睛应该是透明的,可为什么我们看到小白兔的眼
    • 叶乃初
    • 摘要: 就笔者所见到的分析文章和资料,对《木兰诗》中的"雄兔脚扑朔,雌兔眼迷离"这一诗句,几乎全都认定是使用了互文的修辞方式。如果是互文,则可理解为"雌兔雄兔脚扑朔而眼迷离",那么"脚扑朔,眼迷离"便成了雄兔雌兔共有的神态动作特征,这纯属是纸上谈"兔"。凡是饲养过肉兔或长毛兔的人都会知道,成年雄兔静卧时喜欢前脚扑朔,而成年雌兔静卧时则喜欢眼睛半睁半闭,这是它们特有的不同神态动作,并非如课文注释中所讲的"据说",而是确有其神"态"。
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