Hirschsprung病/外科学

Hirschsprung病/外科学的相关文献在2001年到2022年内共计65篇,主要集中在儿科学、临床医学、外科学 等领域,其中期刊论文65篇、专利文献105159篇;相关期刊10种,包括医学临床研究、临床小儿外科杂志、安徽医科大学学报等; Hirschsprung病/外科学的相关文献由225位作者贡献,包括周小渔、刘朝阳、徐兵等。

Hirschsprung病/外科学—发文量

期刊论文>

论文:65 占比:0.06%

专利文献>

论文:105159 占比:99.94%

总计:105224篇

Hirschsprung病/外科学—发文趋势图

Hirschsprung病/外科学

-研究学者

  • 周小渔
  • 刘朝阳
  • 徐兵
  • 李碧香
  • 王忠荣
  • 肖雅玲
  • 苏义林
  • 刘丰丽
  • 吴圣军
  • 周崇高
  • 期刊论文
  • 专利文献

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    • 王吉; 李智
    • 摘要: 先天性巨结肠(Hirschsprung's disease,HSCR)是一种常见的先天性消化道发育畸形,以病变肠管神经节细胞缺乏为特征,发病率约1/5000,男女比例约4∶1。HSCR的治疗主要包括手术治疗和非手术治疗,目前通过手术切除无神经节细胞肠段及移行段仍为HSCR的主要治疗方式。近年来,国内外学者对HSCR非手术治疗进行了深入研究,非手术治疗在HSCR患儿手术前、手术后解决排便问题方面起到了重要作用。本文从扩肛和灌肠、中医药治疗、肉毒素注射治疗、生物反馈治疗以及干细胞治疗等方面对HSCR非手术治疗研究进展进行综述。
    • 李艳丽
    • 摘要: [目的]探讨腹腔镜辅助改良Swenson术式及Soave术治疗短段型小儿先天性巨结肠的近期及远期效果.[方法]选取接受腹腔镜辅助改良Swenson术式或Soave术的80例短段型先天性巨结肠患儿,根据手术方式分为Swenson组、Soave组,每组各40例.比较两组手术指标、术后短期恢复情况、并发症发生情况.随访2年,观察患儿生活质量评分、肛门功能评分、远期并发症发生率.[结果]两组切除肠管长度、术后留置尿管时间、术后进食时间比较,差异无统计学意义(P>0.05);Swenson组术中出血量、手术时间、术后排便频率低于Soave组,术后肠蠕动恢复时间、术后住院时间短于Soave组,差异有统计学意义(P<0.05).两组术后1个月内肛周皮炎、吻合口瘘、盆腔感染、小肠结肠炎、尿潴留发生率比较,差异无统计学意义(P>0.05);Swenson组便秘、粪污、吻合口狭窄发生率低于Soave组,差异有统计学意义(P<0.05).随访2年,两组小肠结肠炎、便秘、粪污发生率比较,差异无统计学意义(P>0.05);两组生活质量及肛门功能优良率均较高,差异无统计学意义(P>0.05).[结论]在短段型小儿先天性巨结肠治疗中,腹腔镜改良Swenson术相比Soave术在近期并发症发生率、术后恢复、术中出血等方面更具优势.
    • 刘朝阳; 周小渔; 尹强; 张雁冰
    • 摘要: 目的 分析经肛门入路根治术治疗对先天性巨结肠患儿免疫功能和肛门功能的影响.方法 选取本院2007年1月至2017年12月收治的先天性巨结肠患儿100例,根据治疗方法不同分为对照组和观察组,每组50例.对照组患儿采用经腹手术治疗,观察组患儿采用经肛门入路根治术治疗,分析两组患儿治疗后的临床效果.结果 观察组患儿术中出血量少于对照组,手术时间、住院时间、胃肠功能恢复时间短于对照组,差异有统计学意义(P<0.05).术前,两组患儿免疫指标比较,差异无统计学意义(P>0.05).术后3d,观察组患儿免疫指标高于对照组,差异有统计学意义(P<0.05).观察组患儿肛门功能总优良率为96.00%,对照组为84.00%,观察组患儿总优良率高于对照组,差异有统计学意义(P<0.05).观察组患儿并发症发生率为6.00%,对照组为20.00%,观察组患儿并发症发生率低于对照组,差异有统计学意义(P<0.05).结论 经肛门入路根治术治疗儿童先天性巨结肠对机体免疫功能影响较小,可以改善患儿的肛门功能,且术后并发症少,安全性高.
    • 刘朝阳; 周小渔; 尹强; 张雁冰
    • 摘要: [目的]探讨经腹会阴根治术对先天性巨结肠患儿的临床效果.[方法]回顾性分析2008年2月至2018年2月本院收治的60例先天性巨结肠患儿的临床资料,根据手术方法的不同将其分为观察组(经腹会阴根治术)和对照组(传统手术),每组各30例.比较两组患儿手术一般情况、术后肠道功能和不良反应发生情况.[结果]观察组术中出血量、术后排气时间、住院时间均小于对照组,差异具有统计学意义(P<0.001);两组手术时间比较,差异无统计学意义(P>0.05).两组手术前肠道功能相关指标比较,差异无统计学意义(P>0.05);观察组术后胃泌素(GAS)、血管活性肽(VIP)和胃动素(MOT)水平高于对照组,差异均具有统计学意义(P<0.001).观察组无不良反应发生,对照组术后不良发生率为10.0%(3/30),两组比较差异无统计学意义(x2=3.158,P=0.076>0.05).[结论]经腹会阴根治术治疗先天性巨结肠患儿临床效果较好,术中出血量较少,可明显改善患儿的肠道功能.
    • 徐兵; 孙传成; 余溪洋
    • 摘要: Objective To explore clinical effects and operative experience of transanal pull-through procedure for Hirschsprung's disease (HD).Methods The clinical data of 126 children aged from 13 days to 14 years with HD were reviewed.There were 30 cases of short-segment type,85 of common type,and 11 of long-segment type.A total of 95 cases was operated with modified Soave and the other 31 cases were operated with modified Swenson.Results Except two-stage resection in 7(5.6%) cases who already underwent transanal Soave procedure early,one-stage transanal pull-through procedure was performed in the other cases.Laparotomy assisted operation was used for 5 cases and laparoscope assisted operation for 12 cases.The complications were occurred in 35 (27.8%) cases post-operation,including 15 perianatitis,9 enterocolitis,5 anastomotic stenosis,2 soiling,and 4 reoperation.The statistical analysis indicated no difference between two procedures and postoperative complications could be noted between different types (P >0.05).A total of 103 patients were followed up from 1 to 10 (mean 2) years.Of all patients,96 (93.2%) were cured,5 (4.9%) symptoms were improved and 2(1.9%) were failed.There were no significant differences in two procedure and the excellent rate of defecation function(P > 0.05).Conclusions Two transanal procedures for HD both had a good efficacy and similar complications.By comparison,transanal Swenson procedure was simpler than Soave procedure,and did not need to enlarge anus post-operation as well.%目的 探讨经肛门巨结肠根治术治疗儿童先天性巨结肠临床疗效及手术技巧.方法 回顾分析经肛门手术治疗126例先天性巨结肠患儿的临床资料,采用经肛改良Soave术95例,经肛改良Swenson术31例.结果 除早期经肛Soave术中7例(5.6%)二期手术外,余均一期完成手术(94.4%).辅助腹部小切口5例,腹腔镜12例.术后并发症35例,其发生率为27.8%,其中肛周糜烂15例,小肠结肠炎9例,吻合口狭窄5例,污粪2例,再手术4例,两种术式的术后并发症比较差异无统计学意义(P>0.05).103例获随访1~10(中位数2)年,痊愈96例(93.2%),好转5例(4.9%),无效2例(1.9%),两种术式不同类型的术后排便功能优良率比较差异均无统计学意义(P>0.05).结论 两种术式治疗先天性巨结肠临床疗效好,各有其优点,均存在一定的并发症,但经肛Swenson术较经肛Soave术操作更简单方便,术后不需扩肛.
    • 许光; 李碧香; 周崇高; 王海阳; 邹婵娟; 朱晟; 王睿
    • 摘要: [Objective] To explore the risk factors of enterocolitis after surgery of Hirschsprung's disease. [Methods] A total of 98 pediatric patients with Hirschsprung's disease undergoing the operation within 3 months in neonate surgery department of children's hospital of Hunan province from Jan. 2009 to Dec. 2010 were chosen. Univariate logistic regression and multifactor logistic regression analysis were used to analyze the risk factors of enterocolitis after operation. [Results] Among 98 pediatric patients, 78 patients(79. 6%) were male and 20 patients(20. 4%) were female. The 96 patients(98%) were cured, and 2 patients(2%) died. The 20 patients(20. 4%) were complicated with enterocolitis after operation. Univariate logistic regression analysis showed that the main risk factors of complicated enterocolitis were malnutrition, intestinal obstruction, milk allergy, pneumonia, hypoganglionosis and septicemia. Multifactor logistic regression analysis showed that the risk factors were malnutrition, intestinal obstruction, hypoganglionosis and pneumonia. [Conclusion] Enterocolitis is the common and serious complication for Hirschsprung's disease after operation. Malnutrition, intestinal obstruction, hypoganglionosis and pneumonia may be the independent risk factors of enterocolitis after operation. Improving nutrition, removing intestinal obstruction and protecting mucous membrane of pediatric patients can reduce the incidence of the complication.%[目的] 探讨先天性巨结肠术后并发小肠结肠炎的危险因素.[方法] 选取湖南省儿童医院2009年1月1日至2010年12月31日期间在新生儿外科住院的年龄3个月内经手术治疗的先天性巨结肠患儿98例.采用单因素logistic回归和多因素logistic回归统计分析术后并发小肠结肠炎的危险因素.[结果] 98例患儿中,男78例(79.6%);女20例(20.4%).治愈96例(98%);死亡2例(2%).20例(20.4%)术后发生小肠结肠炎,单因素logistic回归分析表明,并发小肠结肠炎的危险因素主要是营养不良、肠梗阻、牛奶过敏、肺炎、肠神经节细胞减少和败血症.多因素logistic回归分析表明,其危险因素主要是营养不良、肠梗阻、肠神经节细胞减少和肺炎.[结论] 小肠结肠炎是先天性巨结肠术后常见而且严重的并发症,营养不良、肠梗阻、肠神经节细胞减少和肺炎可能是术后小肠结肠炎的独立危险因素.改善患儿营养状况,解除肠梗阻因素和保护肠道黏膜可减少该并发症的发生.
    • 黄河; 戚士芹; 高群; 陈晨; 卢贤映; 未德成
    • 摘要: Objective To summarize the experiences of laparoscopic-assisted with modified Soave' s procedures for Hirschsprung's disease in children. Methods From February 2007 to October 2011, 42 cases with Hirshsprung' s disease were performed with laparoscopic-assisted with modified Soave' s procedures and the operative experiences were summarized. Results All cases had successfully operations without conversion to laparotomy. The mean duration of the procedure was 150 min and postoperative hospital stay was 7 d. There .were no recent complications associated with laparoscopic procedure and no stool incontinence or recurrent constipation after long-term follow-up. Conclusions Laparoscopic-assisted with modified Soave' s procedure is safe and effect for Hirschsprung's disease with minimally invasive surgery features and should be advocated actively.%目的 总结腹腔镜辅助改良Soave术根治小儿先天性巨结肠的临床经验.方法 回顾性分析2007年2月至2011年10月作者收治的42例先天性巨结肠患儿临床资料,对操作经验进行总结.结果 全部病例均手术成功,无中转开腹病例,平均手术时间150 min,术后平均住院时间7d,无腹腔镜操作相关的近期并发症,远期随访无污粪和便秘复发.结论 腹腔镜辅助改良Soave根治术治疗先天性巨结肠安全有效,具有微创效果,值得推广.
    • 钟微; 余家康; 夏慧敏; 孙静; 朱士博; 李瑞琼; 何秋明; 王勇; 李乐
    • 摘要: 目的 评估回肠拖出Soave术治疗全结肠型巨结肠患儿的肛门直肠功能、营养状况及中远期疗效.方法对1999年1月至2010年12月经手术治疗的8例接受直接回肠拖出Soave术的全结肠型巨结肠患儿进行随访,随访时间18~147个月,平均随访时间(62.5±44.0)个月;均行体格测量及实验室检查的营养评估;采用间卷进行直肠肛门功能Kelly评分及生活质量评分.结果 8例患儿中,4例(50%)肛门外形正常,4 例(50%)肛周轻度糜烂;4例(50%)排便次数3~5次/d;8例直肠肛门功能Kelly评分3~6(5.1±1.0)分,7例(87%)获得较满意评分.生活质量评分7~11(9.6±1.2)分.疗效优6例(75%).对7例10岁以下患儿采用WHO评估标准,其中年龄别身高正常4例(57.1%),轻度营养不良2例(28.6%),中度营养不良1例(14.3%).结论回肠拖出Soave术治疗全结肠型巨结肠患儿术后中远期疗效满意,虽轻、中度营养不良的发生率较高,但大部分患儿发育正常.%Objective To investigate the long-term results of total colonic aganglionosis and to evaluate their nutritional status. Methods eight patients treated for TCA between January 1999 and December 2010 attended the study. Eight patients received straight ileo-anal pull-through. During the follow-up(range 18 ~ 147 months,average 62.5 ±44 months) ,anorectal functions with Kelly score,quality of life ( QOL) ,height,weight and lab tests were assessed by clinical visit. Results The average KeUy score was 5. 1 ± 1. 0( range 3 ~ 6) , seven patients (87% ) had satisfactory anorectal functions. QOL was good in six patients(75% ) , average score was 9.6 ±1.2. According to the WHO standard for children less than ten years old,in terms of height-for-age (HFA) ,57. 1% and 28. 6% were normal and mild malnutrition whereas 14. 3% was medium malnutrition in seven patients. Conclusions Patients with TCA can have satisfactory outcomes on long-term follow up. How-ever,mild and medium malnutrition were common in these patient.
    • 徐兵; 孙传成; 孙华; 苏义林; 王忠荣
    • 摘要: Objetive To compare the advantages and disadvantages between trananal modified Swenson and Soave procedure for Hirschsprung's disease (HD). Methods The clinical data of 50 children with HD from. 2007. 1 to 2011. 12 were reviewed. There are 13 cases of short-segmend type, 33 common type and 4 long-segment type. 21 of the 50 cases operated by modified Swenson and the other 29 cases operated by modified Soave. Surgery events, complications and defecation function in 6 months after operation were compare respectively. Results There were no significant differences in preoperative enema days, intraoperative blood loss, inpatient days after operation, defecation frequency on discharged between the two groups(P > 0. 05). The operative time of Swenson procedure is shorter than that of Soave procedure (P < 0. 05). Postoperative complications were 19. 0% and 37. 9% respectively, while the defecation function of excellent rate were 95.2% and 89.6% in postoperative 6 months. Conclusions The two trananal procedures both have the advantage of small wound, swift recovery and good efficacy. Comparatively speaking,trananal Swenson procedure is simpler and with fewer complications than Soave procedure. Because of laparoscopic-assisted surgery increase , both procedures are suitable for young and older children.%目的 比较经肛门改良Swenson术和Soave术治疗先天性巨结肠的疗效及优缺点.方法 回顾性分析经肛门手术治疗的50例先天性巨结肠患儿临床资料,其中短段型11例,普通型35例,长段型4例;行经肛门改良Swenson术21例,经肛门改良Soave术29例.比较两组患儿手术相关因素、术后并发症及排便功能情况.结果 两种术式术前灌肠时间、术中出血量、术后住院天数及出院时排便情况比较,无统计学意义(P>0.05),而手术时间比较,前者较后者短(P<0.05).两组术后并发症的发生率分别为19.0%和37.9%,术后6个月时排便优良率为95.2%和89.6%.结论 经肛门改良Swenson术和改良Soave术创伤小,恢复快,疗效好,但经肛门Swenson术较经肛门Soave术操作更简单方便,并发症明显减少;两者手术适应证均可适当放宽.
    • 樊长河; 张中喜
    • 摘要: 目的探讨经肛门改良Soave巨鲒肠根治术后患儿肛门功能及直肠肛管测压改变情况。方法对我院38例经肛门改良Soave巨结肠根治术患儿回顾性分析其肛门功能及肛门直肠测压结果比较.术后平均随访3a(6个月-4a)。结果经肛门改良Soave巨结肠根治术后排便控制良好;直肠肛管抑制反射恢复率偏低,但直肠静息压、感觉阈值和最大直肠耐受容量均较术前有明显改善。结论经肛门改良Soave巨结肠根治术创伤小、术后可获得良好的排便控制。
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