Globus

摘要： 科研数据的爆发式增长和远程共享对数据管理提出需求,可实现弹性扩展、高性能传输、云托管的微服务架构数据管理平台为数据的高效管理提供可能.本文调研分析了芝加哥大学阿贡国家实验室研究团队研发的Globus科研数据管理平台.该平台采用分布式微服务架构,包括身份管理、组群服务、数据传输和数据共享4个微服务模块,模块之间相互独立,通过可视化Web界面实现科研数据的传输和共享.该平台已经应用于多个科研项目的数据管理,完成TB数量级的文件传输,其跨区域高效传输、灵活共享的数据管理模式可为我国科研数据管理提供借鉴.

摘要： 介绍了OGSA-DAI体系结构工具包Globus,列出了Globus的体系结构,分析了GT4的体系结构,为Globus的应用奠定了基础.

摘要： POP、FVCOM、HYCOM为三种使用较为广泛的海洋数值模式,并且都具有可并行性,为了提高计算和执行效率,提出使用校园网格平台来实现.河海校园网格平台采用了WSRF、OGSA网格技术和三层结构,通过Portal、Shell和远程图形工具进行任务提交,并成功实现了POP、FVCOM、HYCOM模式的并行计算.实际应用表明,基于该平台的三种海洋数值模式计算时间缩短了6倍以上,并行效率超过了80％.

摘要： Heterotopic gastric mucosa of the proximal esophagus (HGMPE),also referred to as"inlet patch"or"cervical inlet patch",is a salmon colored patch that is usually located just distal to the upper esophageal sphincter. HGMPE is uncommon with endoscopic studies reporting a prevalence ranging from less than one percent to 18%.Most HGMPE are asymptomatic and are detected incidentally during endoscopy for evaluations of other gastrointestinal complaints.Most consider HGMPE as clinically irrelevant entity.The clinical significance of HGMPE is mainly acid related or neoplastic transformation.The reported prevalence of laryngopharyngeal reflux symptoms varies from less than 20%to as high as 73.1%.However,most of these symptoms are mild. Clinically significant acid related complications such as bleeding,ulcerations,structure and fistulization have been reported.Although rare,dysplastic changes and malignancies in association with HGMPE have also been reported.Associations with Barrett's esophagus have also been reported but the findings so far have been conflicting.There are still many areas that are unknown or not well understood and these include the natural history of HGMPE,risk factors for complications,role of Helicobacter pylori infection and factors associated with malignant transformations.Follow-up may need to be considered for patients with complications of HGMPE and surveillance if biopsies show intestinal metaplasia or dysplastic changes.Despite the overall low incidence of clinically relevant manifestations reported in the literature,HGMPE is a clinically significant entity but further researches are required to better understand its clinical significance.

摘要： AIM:To compare the efficacy and side effects of lowdose amitriptyline(AMT)with proton pump inhibitor treatment in patients with globus pharyngeus.METHODS:Thirty-four patients who fulfilled the RomeⅢcriteria for functional esophageal disorders were included in this study.Patients were randomly assigned to receive either 25 mg AMT before bedtime(AMT group)or 40 mg Pantoprazole once daily for 4 wk(conventional group).The main efficacy endpoint was assessed using the Glasgow Edinburgh Throat Scale(GETS).The secondary efficacy endpoints included the Medical Outcomes Study 36-item short form health survey[social functioning(SF)-36]and the Pittsburgh Sleep Quality Index.Treatment response was defined as a>50%reduction in GETS scores.All patients entering this study recorded side effects at days 1,8,15,22 and 29 using a visual analogue scale.RESULTS:Thirty patients completed the study.After 4 wk of treatment,the AMT group had a greater response than the conventional group(75%vs 35.7%,P=0.004).At day 3,the AMT group showed significantly more improvement than the Conventional group in GETS score(3.69±1.14 vs 5.64±1.28,P=0.000).After 4 wk of treatment,the AMT group showed significantly greater improvement in GETS score and sleep quality than the Conventional group(1.25±1.84 vs 3.79±2.33,4.19±2.07 vs 8.5±4.97;P<0.01 for both).Additionally,the AMT group was more likely than the Conventional group to experience improvement in the SF-36,including general health,vitality,social functioning and mental health(P=0.044,0.024,0.049 and 0.005).Dry mouth,sleepiness,dizziness and constipation were the most common side effects.CONCLUSION:Low-dose AMT is well tolerated and can significantly improve patient symptoms,sleep and quality of life.Thus,low-dose AMT may be an effective treatment for globus pharyngeus.

摘要： AIM: To investigate the effect of rikkunshito on laryngopharyngeal reflux(LPR) symptoms and gastric emptying in patients with proton-pump inhibitor(PPI)refractory LPR.METHODS: In total,22 patients with LPR were enrolled.Following a 2-wk treatment with PPI monotherapy,PPI-refractory LPR patients were randomly divided into two treatment groups(rikkunshito alone or rikkunshito plus the PPI,lansoprazole).LPR symptoms were assessed using a visual analog scale(VAS) score,gastrointestinal symptoms were assessed using the gastrointestinal symptom rating scale(GSRS),and gastric emptying was assessed using the radio-opaque marker method prior to and 4 wk following treatments.RESULTS: The 4-wk treatment with rikkunshito alone and with rikkunshito plus the PPI significantly decreased the globus sensation VAS scores.The VAS score for sore throat was significantly decreased following treatment with rikkunshito plus PPI but not by rik kunshito alone.Neither treatment significantly changed the GSRS scores.Rikkunshito improved delayed gastric emptying.We found a significant positive correlation between improvements in globus sensation and in gastric emptying(r2= 0.4582,P < 0.05).CONCLUSION: Rikkunshito improved globus sensation in patients with PPI-refractory LPR,in part,because of stimulation of gastric emptying.Thus,rikkunshito is an effective treatment for PPI-refractory LPR.

摘要： 网格计算粗粒度的管理方式导致的网格体系僵化带来了诸多不便,成为网格计算在科研领域更深入应用的阻碍.采用虚拟组织的思想,提出了动态虚拟组织管理方案来针对网格计算项目进行细粒度管理.该方案按照虚拟组织的方式管理多个网格计算项目,以虚拟组织成员关系控制用户访问的权限,使得虚拟组织的构成更加灵活.针对Globus网格平台设计了动态虚拟组织管理系统,实际应用表明该系统实现了细粒度的多网格管理,证明了动态虚拟组织管理方案的有效性.%The innate coarse-grained management of grid computing leads to inflexible structure, which brings about much inconvenience and inhibits a broader application of grid computing. With the virtual organization concept, this paper proposes a dynamic virtual organization management scheme which provides fine-grained project management to solve this problem. This scheme manages grid projects as different virtual organizations and controls user access according to membership relations in virtual organizations. Above the Globus grid system, the paper develops a dynamic virtual organization management system. It also gives a case to demonstrate the effectiveness of this scheme for fine-grained dynamic management of multiple grid systems.

摘要： 税务系统发票数据电子信息分散存放在全国各个省市的服务器数据库中,数据量达到了海量数据,而各省市之间税务发票电子信息却相互隔离,在税务系统内部形成了一个个的税务发票电子信息“孤岛”,对于跨地区使用的税务发票的大部分脱离了税务机关的监控；海量的发票数据信息没有得到充分的利用；社会公众缺乏统一的税务发票真假辨别平台,数据网格技术的引入给解决这一问题提供了新的解决方案.论文首先对当前阶段国内外税务系统信息化与发票管理的现状作对比,对税务发票实际管理的现状进行了分析,论述了数据网格技术在税务系统发票管理中应用的现实意义.其次,在研究了目前网格技术理论及成果的基础上,提出构建基于Glob1m和OGSA-DAI的税务发票网格系统(TIG).最后论文对进行了异构数据库连接进行了模拟测试.%The electronic information of invoice data in tax system scatters the server database of various provinces and cities in our country, and the data is mass. However, the electronic information of invoice data among various provinces and cities is separate from each other, which forms "information island" in tax system, and it breaks away from the monitoring of the tax authorities for tax invoice which is used trans-regionally. Mass invoice data information has not been fully utilized; there are no a platform for social publics to distinguish tax invoice, and the introduction of data grid technology provides the new solutions to solve the problems-Firstly, this paper made a contrast on the current status between informatization of tax system and invoice management at home and abroad, analyzes the present situation of the actual management of tax invoice, and discusses the realistic significance for applying the data grid technology in tax invoice management Secondly, the tax invoice grid systemfTIG) is constructed based on Globus and OGSA-DAI on the basis of studying on the theory and results of current grid technology. Finally, the paper conducts simulation tests on heterogeneous database connection.

摘要： 介绍科学数据的特点和信息孤立现象产生的原因与现状,并通过研究OGSA-DAI项目的框架结构与原理,分析了根据其构建科学数据共享平台的可行性.最后提出以OGSA-DAI+Globus(Open Grid Services Architecture-Data Access And Integration)数据网格环境为基础,构建安全的、跨地域、跨平台的科学数据共享平台的解决方案.%The paper introduces scientific data characteristics as well as forming reasons and circumstances of information isolation phenomenon. In addition, through studying OGSA-DAI project framework architecture and principles, the feasibility of building a scientific data sharing platform upon it is analyzed. Finally, a solution is proposed to construct a secure, cross-regional and cross-platform scientific data sharing platform based on OCSA-DAI plus a Globus data grid environment.

摘要： It took many centuries for the basal ganglia (BG) to be recognized as specific brain entities involved in the control of psychomotor behavior. Andreas Vesalius (1514-1564) was the first to delineate this set of structures, but he did not name them nor payany attention to their functional significance. This was left to the English physician Thomas Willis (1621-1675), who used the term corpus striatum (striated or chamfered body) to designate the largest BG constituent, which he considered a major sensorimotor integration center. Willis’s pioneering description influenced markedly some 18th and 19th centuries scholars, particularly the German physician and anatomist Karl Friedrich Burdach (1776-1847). Burdach’s insightful studies of the human brain are summarized in a three-volume treatise entitled Vom Baue und Leben des Gehirns (1819-1826). This landmark opus provides a description of the BGwhose originality has largely been overlooked. Burdach’s careful investigation allowed him to differentiate the caudate nucleus from the putamen, which he respectively termed Streifenhügel (elongated hillock) and Schale (shell). He also called the putamen Linsenkern (lens-shaped nucleus), a term that he admittedly borrowed from his compatriot Johann Christian Reil (1759-1813). He further identified a paler structure (blasser Klumpen) within the inner portion of the lentiform nucleus that he called globus pallidus, and correctly identified its inner and outer segments (innern und ?ussern Theil). He aptly pointed out that the major BG nuclei are separated from one another by fibers fascicles that he termed inner and ?ussre Capsel (internal and external capsules). Burdach also referred to the substantia nigra (schwarzgraue Schicht or stratum nigrum) and claustrum (Vormauer), but gave full credit to the French anatomist Félix Vicq-d’Azyr (1748-1794) for their discovery. Although Burdach did not comment much on BG function, his anatomical description was sufficiently cogent to be still in use two centuries after its inception.

摘要： 首先将arc和现有的使用最为广泛的globus做了简单的比较,深入探讨的arc的性能优点以及各个组件之间的逻辑联系,并进一步的分析arc的实现要点以及在系统的运行过程中的注意事项,文章最后给出了arc目前还没有解决的问题,并提出了自己的看法和改进的意见.

摘要： 随着计算机和网络技术的发展以及大规模计算需求的日益增加，网格(Grid)技术应运而生。目前面向服务的网格技术已经成为该领域研究的热点问题。以CGSP(ChinaGrid Support Platform)中间件作为公共支撑平台，对基于CGSP的Web服务设计与实现进行了较为深入的研究，并通过天气查询服务实例进一步说明该服务的具体实现过程。

摘要： 随着计算机和网络技术的发展以及大规模计算需求的日益增加，网格(Grid)技术应运而生。目前面向服务的网格技术已经成为该领域研究的热点问题。以CGSP(ChinaGrid Support Platform)中间件作为公共支撑平台，对基于CGSP的Web服务设计与实现进行了较为深入的研究，并通过天气查询服务实例进一步说明该服务的具体实现过程。

摘要： 随着计算机和网络技术的发展以及大规模计算需求的日益增加，网格(Grid)技术应运而生。目前面向服务的网格技术已经成为该领域研究的热点问题。以CGSP(ChinaGrid Support Platform)中间件作为公共支撑平台，对基于CGSP的Web服务设计与实现进行了较为深入的研究，并通过天气查询服务实例进一步说明该服务的具体实现过程。

摘要： 随着计算机和网络技术的发展以及大规模计算需求的日益增加，网格(Grid)技术应运而生。目前面向服务的网格技术已经成为该领域研究的热点问题。以CGSP(ChinaGrid Support Platform)中间件作为公共支撑平台，对基于CGSP的Web服务设计与实现进行了较为深入的研究，并通过天气查询服务实例进一步说明该服务的具体实现过程。

摘要： 网格是一种新兴的技术,网格计算可以实现资源、计算和服务的全面共享,是分布式计算的发展趋势。本文论述了资源调度器Condor和构建网格基础设施的工具Globus Toolkit各自的特点,以及如何使用Condor-G完成网格任务的提交,实现网格计算。

摘要： 网格是一种新兴的技术,网格计算可以实现资源、计算和服务的全面共享,是分布式计算的发展趋势。本文论述了资源调度器Condor和构建网格基础设施的工具Globus Toolkit各自的特点,以及如何使用Condor-G完成网格任务的提交,实现网格计算。

摘要： 网格是一种新兴的技术,网格计算可以实现资源、计算和服务的全面共享,是分布式计算的发展趋势。本文论述了资源调度器Condor和构建网格基础设施的工具Globus Toolkit各自的特点,以及如何使用Condor-G完成网格任务的提交,实现网格计算。

摘要： 网格是一种新兴的技术,网格计算可以实现资源、计算和服务的全面共享,是分布式计算的发展趋势。本文论述了资源调度器Condor和构建网格基础设施的工具Globus Toolkit各自的特点,以及如何使用Condor-G完成网格任务的提交,实现网格计算。

摘要： 网格是一种新兴的技术,网格计算可以实现资源、计算和服务的全面共享,是分布式计算的发展趋势。本文论述了资源调度器Condor和构建网格基础设施的工具Globus Toolkit各自的特点,以及如何使用Condor-G完成网格任务的提交,实现网格计算。