摘要：
目的 探讨复方丹参注射液联合低分子右旋糖苷治疗小儿脑动脉炎的的疗效.方法 2011年1月至2014年12月河南商丘人民医院儿科脑动脉炎的30例患儿随机分为治疗组(15例)和对照组(15例),对照组给予常规抗病毒和营养神经治疗,治疗组在常规治疗的基础上,给予复方丹参注射液6~20 mg,同时加用低分子右旋糖苷10 ml/kg,静脉滴注,1次/d,部分颅内压增高患儿,给予20%的甘露醇,2~5 ml·kg-1·次-1, 1次/12 h,或短期加用地塞米松进行治疗,持续用药2~4周,观察两组治疗效果和复发情况.结果治疗组14例有效,总有效率93.3%,对照组10例有效,总有效率66.7%,两组复发率分别为6.7%和26.7%,差异均有统计学意义(χ2=2.160,P<0.05).结论 丹参注射液联合低分子右旋糖酐治疗小儿脑动脉炎疗效满意,有效扩张脑动脉的同时可对红细胞聚集和血栓的形成达到一定的预防作用,患者大多预后良好,复发率低.%Objective To investigate the Danshen injection combined with low molecular weight dextran therapy of children with cerebral arteritis.Methods From January 2011 to December 2014 in children cerebral arteritis Shangqiu City, Henan Province People's Hospital treated 30 patients were randomly divided into treatment group (15 cases) and control group (15 cases), the control group received conventional anti-virus and neurotrophic treatment group on the basis of conventional therapy, giving Danshen injection 6 ~ 20 mg, while the addition of dextran 10 ml / kg, intravenous infusion, 1 times/d, part of the intracranial pressure increased in children, giving a 20% mannitol, 2 ~ 5 ml/kg each,1 times/12 h, or short-term dexamethasone treatment, continuous medication 2 to 4 weeks of treatment were observed effects and recurrence.Results Effective treatment group 14 cases, the total effective rate was 93.3% in the control group, 10 cases effective, the total efifciency of 66.7%, two recurrence rate was 6.7% and 26.7%, respectively, the differences were statistically signiifcant(χ2=2.160,P<0.05). Conclusions The curative effect of Danshen injection combined with low molecular dextran in treatment of children with cerebral arteritis satisfaction, at the same time effective expansion of cerebral artery can be formed to achieve certain preventive effects on erythrocyte aggregation and thrombosis, most patients with good prognosis, recurrence rate.
