factors

摘要： The aim of the study is to assess the factors that influence the sustainability of agricultural development. The study was carried out in the municipality of Bobonaro for about four months, from July to October 2021. Slovin’s method was used to determine the sample size, with a desired percentage of 10% of the total population. Thus, 154 producers were interviewed as respondents and key persons in the area of agriculture. The variables interviewed are the main factors of agricultural productivity and the factors that affect sustainable agricultural development. The results of the descriptive statistical analysis of the data showed that about 94.87% of the respondents’ productive area is in operation, with an average of 1.84 ha per respondent and the abandoned area around 0.11 ha per respondent. The average value of rice production is 2.38 ton per ha and corn 1.07 ton per ha. About 87% of producers raised the main types of animals such as cattle, pigs, goats with an average density of 2 to 5 animals per establishment. About 61% of producers have access to the market at a normal price for agricultural products. The factors that hinder less successful agricultural development, such as: those of nature with the greatest impact are climate changes, which influence changes in cultivation sessions and in the characteristics of productive soils, availability of water for irrigation and animal feed. On the socioeconomic side, it includes the willingness or interest of young people who want to work as farmers, less investment and the impact of the Covid-19 pandemic. It is concluded that natural and socioeconomic impacts can reduce agricultural productivity, so that this will be a major challenge for the development of the agricultural sector in the future.

摘要： Introduction:Understanding the causes of heart disease is a relatively new field in medicine.In fact,heart disease was relatively rare before the early 1900s.Aim:The aim of this review study is to investigate the risk factors associated with the development of heart disease and its prevention.Material Methodology:A scrutinized review of the Greek and international literature was carried out.The material of the study was manuscripts on the subject found in Greek and international electronic databases such as:Google Scholar,Mednet,PubMed and the Association of Hellenic Academic libraries(HEAL-Link).Results:The risk factors for the development of heart disease are metabolic factors,i.e.,hypertension,diabetes,cholesterol and obesity;environmental factors,i.e.,smoking,lack of physical activity or exercise,poor dietary patterns and alcohol consumption;and other factors such as age,gender,heredity,socioeconomic status and psychological factors.Conclusions:Heart diseases are multifactorial diseases and the only way to successfully treat them is to take into account all the risk factors for their development,and to treat them systematically.

摘要： Objective:To assess and compare the relationship between spousal communication,fertility preference,and other factors with contraceptive use among married couples in Ekiti State,Nigeria.Methods:This cross-sectional study was carried out in AdoEkiti Local Government Area of Ekiti State,Nigeria between the 12th of August 2017 and the 15th of February 2018.A pre-tested,semi-structured interviewer-administered questionnaire was used to collect data from 976 respondents by a multi-stage sampling technique.Data were analyzed(univariate,bivariate,and binary logistic regression analysis)using SPSS version 24.0.Factors that showed statistical significance(P<0.05)were included in a binary logistic regression to determine significant predictors of contraceptive use.Results:The proportion of respondents currently using contraceptives was 56.9%.The education status of the respondents revealed that those with primary education were more likely to use contraceptives than those without formal education[adjusted odds ratio(aOR)8.4,95%confidence interval(CI)1.97-36.2,P<0.001].Respondents with fair spousal communication were more likely to use contraceptive than those with poor communication(aOR 4.9,95%CI 2.80-8.71,P<0.001).In addition,fertility preference of 4 or less children was found to be significantly associated with contraceptive use(aOR 3.0,95%CI 1.67-5.50,P<0.001)compared to a preference of more than 4 children.Finally,the urban respondents were more likely to use contraceptives than those in the rural setting(aOR 1.7,95%CI 1.16-2.41,P=0.047).Conclusions:Educational status,residential site,spousal communication,and fertility preference significantly influence the level of contraceptive use among married couples.Couples should endeavor to discuss more on issues bordering on their fertility preference and contraceptive issue.Government should formulate policies to improve the rural uptake of contraceptives using identified target interventions.

摘要： Research self-efficacy is of great significance for teachers to improve their interest and achievements in scientific research.In this study,261 elementary teachers were surveyed through online questionnaires to understand their research self-efficacy.The results showed that most elementary teachers have good research self-efficacy;education background,years of teaching,research environment,and attitude toward research all had influence on the research self-efficacy of elementary teachers.Based on this situation,schools should make efforts,such as improving communication,providing financial support,establishing a scientific research support center,and helping teachers under unfavorable situations.For elementary teachers,they should realize the importance of education research and improve their research literacy。

摘要： Background: Breast cancer has become an important disease burden harmful to women’s health. The treatment of breast cancer is mainly surgical treatment. In the context of enhanced recovery after surgery, the average length of hospital stay has been reduced, so there is increasing concern about postoperative patient discharge readiness. Objective: To identify factors influencing readiness for hospital discharge among patients having undergone breast cancer surgery and to explore the relationship between discharge readiness and the quality of discharge teaching. Methods: A total of 99 patients after breast cancer surgery at a regional tertiary medical tumor center in Guangzhou between June 2021 and December 2021 were collected using the convenience sampling method. A general data questionnaire, readiness for hospital discharge scale, and quality of discharge teaching scale were used to conduct a questionnaire survey on the subjects. Results: 83.8% of the patients feel ready for discharge, and the score of discharge readiness was 155.98 ± 28.87. The patients’ content received and the skills in teaching delivery were the influencing factors of discharge readiness. Discharged with a drainage tube was an independent factor of discharge readiness. Conclusions: Readiness for hospital discharge among patients undergoing breast cancer surgery was above medium level, and perfect intervention measures should be formulated for the influencing factors of discharge readiness. Especially, specific executable safeguard measures should be formulated for patients who are discharged early after surgery to promote the safety of home care.

摘要： Objective:To explore the nurses’behaviors regarding clinical alarms,analyze the related influencing factors,and provide rationales for alarm management.Methods:A cross-sectional survey was conducted in China.The self-made questionnaire of nurses’clinical alarm-related knowledge,attitude,and behavior(NCAKAB)was used.Results:The valid response rate was 98.66%(n=2368).The average nurses’clinical alarm-related behaviors(NCAB)score was 65.14±7.95(out of 85).The dimension scores of NCAB from high to low were alarm learning(4.02±0.85,out of 5),alarm response(27.99±3.64,out of 35),alarm setting(19.24±3.88,out of 25),alarm recognition(7.63±1.68,out of 10)and alarm notification(6.25±1.84,out of 10).There were significant differences in alarm behavior scores between nurses of different ages(F=4.619,P=0.000),nursing stints(F=9.564,P=0.000),professional titles(F=4.425,P=0.004),departments(F=9.166,P=0.000),and hospital levels(t=2.705,P=0.007).The study showed that nurses’total alarm behavior scores were positively correlated with the total alarm knowledge score(r=0.267;P<0.001)and the total alarm attitude score(r=438;P<0.001).Conclusions:Nurses scored highest in alarm learning,followed by alarm response,alarm setting,alarm recognition,and alarm notification behavior.The factors that influenced alarm behavior included age,title,department,nursing stint,hospital level,professional title,alarm-related training,willingness to participate in alarm-related training,whether or not departments have improved alarm management over the last 3 years,and whether or not departments have formulated norms for alarm management.Nurses with higher scores for clinical alarm knowledge had higher correlating scores for alarm behavior;similarly,nurses with higher scores for clinical alarm attitude had higher scores for alarm-related behavior.

摘要： BACKGROUND The factors influencing the prognosis of patients with esophageal cancer vary among studies and are still poorly known.AIM To determine the factors associated with survival in patients with esophageal cancer.METHODS This retrospective study included patients with esophageal cancer admitted between January 2017 and March 2020 at Heping Hospital Affiliated to Changzhi Medical College. All patients were treated according to the available guidelines. Follow-up was censored in October 2020. Univariable and multivariable Cox regression analyses were used to determine the independent risk factors for overall survival(OS).RESULTS In total, 307 patients were included. Their median age was 64(range, 44-79) years, 63.5% were male, and the median disease course was 2(0.1-36) months. The median tumor size was 3(0-10) cm. Most patients were T3(29.6%), N0(70.0%). Most tumors were grade 2(48.2%), and 87.3% were squamous cell carcinoma. The in-hospital mortality was 16.9%, the 30-day mortality was 19.9%, and the 90-day mortality was 25.4%. The cumulative OS rates at the last follow-up were 82.1%(95%CI: 67.7%-96.5%) for stage 0/Ⅰ/Ⅱ and 47.4%(95%CI: 16.5-78.6%) for stage Ⅲ/ⅣA(P < 0.001). The multivariable analysis showed that creatinine levels(HR = 1.02, 95%CI: 1.00-1.03, P = 0.050), pTNM Ⅲ/ⅣA(HR = 4.19, 95%CI: 2.19-8.01, P < 0.001), adjuvant radiotherapy and/or chemotherapy(HR = 0.23, 95%CI: 0.11-0.49), and the Comprehensive Complication Index(CCI)(HR = 1.02, 95%CI: 1.004-1.03, P = 0.011) were independently associated with OS.CONCLUSION The survival of patients with esophageal cancer is poor, especially those with pTNM Ⅲ/ⅣA. pTNM stage Ⅲ/ⅣA, CCI, and adjuvant therapy(radiotherapy and/or chemotherapy) are independently associated with OS.

摘要： Background: The coronavirus disease 2019 (COVID-19) is a public health problem that has caused harm to the mental health of healthcare workers. In Africa, the COVID-19 pandemic has led healthcare workers to experience mental health disorders such as anxiety, depression, stress, insomnia and burnout. This study aimed to review published studies on the effect of COVID-19 on the mental health of healthcare workers, associated factors and coping strategies that have been employed in Africa. Methods: This was a systematic review that was conducted through searching databases including;PubMed/Medline and Google Scholar. The study included published literature from January 2020 to May 2022 that met the inclusion criteria. The selection of articles was conducted following the 2020 PRISMA guidelines. Results: A total of 39 articles were retrieved, of which only 18 met the inclusion criteria and were used in this study. Our review revealed that healthcare workers experienced mental health disorders such as anxiety, depression, insomnia, stress and burnout that were associated with the COVID-19 pandemic. Coping strategies such as religious practices, support from family members and colleagues and avoiding listening to social media about COVID-19 were used to minimize mental health problems. Conclusion: The COVID-19 pandemic has caused increased mental health disorders among healthcare workers in Africa. Identification of factors associated with mental health problems is cardinal in developing coping mechanisms against the psychological impact of COVID-19. Therefore, there is a need for governments to develop and implement strategies for protecting the mental health of healthcare workers during crises such as the COVID-19 pandemic.

摘要： Objective:Quality by design integration is exceedingly imperative for industries dealing with pharmaceuticals,but it diminishes product variability and delivers an extraordinary degree of assurance that the product would achieve the purpose for which it was formulated.The objective of the manuscript is to strengthen the understanding of the design of experimentation approach from the primary level.Hence,this review paper aims to get one experience with a course emphasizing product quality during its development process.Methods:The present work describes how experimental statistical designs can optimize the process.It is a strategy to improve the manufacturing of products and discuss the main factors involved in the production.The review describes different designs,advantages,disadvantages and design of experiments requirements concerning regulatory submissions.Results:Quality by design encourages the pharmaceutical industry to deal with risk management and proper understanding of products and manufacturing processes,assuring a good quality product.Having knowledge of quality by design and design of experiments in the formulation and process development will be beneficial for the optimization of drug delivery systems in upcoming times.Conclusion:Implementing quality by design at different phases in pharmaceutical manufacturing,the final product with a great degree of reproducible quality may be assured,depending upon experimental data.This contains valuable information in guiding new researchers about the importance and ways of using the design of experiments.

摘要： With the establishment of a well-off society in an all-round way,Chinese residents have put forward higher requirements for the quality and safety of fresh agricultural products.In recent years,domestic and foreign academic circles have also paid more and more attention to the risk of fresh agricultural product supply chain.This article collects and sorts out the research findings of domestic and foreign scholars on the risk assessment of fresh agricultural product supply chain in recent years,and summarizes and discusses from three aspects:supply chain risk factors,risk assessment indicator selection,and risk assessment methods.It is intended to provide a reference for future new research ideas and research perspectives.

摘要： 本发明公开了一种Factor II和Factor V基因多态性检测特异性引物和液相芯片，该液相芯片主要包括有：每种由5’端的tag序列和3’端针对目的基因突变位点的特异性引物序列组成的ASPE引物，所述特异性引物序列为：针对Factor II基因A140G位点的SEQ ID NO.7及SEQ ID NO.8；针对Factor II基因G78A位点的SEQ ID NO.9及SEQ ID NO.10；和/或针对FactorV基因G125A位点的SEQ ID NO.11及SEQ ID NO.12；有anti-tag序列包被的微球；扩增引物。本发明所提供的检测液相芯片的检测结果与测序法的吻合率高达100％，实现多个突变位点的野生型和突变型并行检测。

摘要： 本申请实施例公开了一种计算Q‑Factor的电路、方法、装置及电子设备，用于提高Q‑Factor的精确度。本申请实施例为：滤波电路、谐振网络、第一检测电路和控制电路；滤波电路包括第一电阻R1、第二电阻R2、第三电阻R3、第一电容C1、第二电容C2、放大器和比较器；谐振网络分别与控制电路和第一电阻R1第一端连接，第一电阻R1的第二端与放大器连接；放大器分别与第二电阻R2第一端和第三电阻R3第一端连接；第二电阻R2第二端分别与第一电容C1的第一端和比较器第一输入口连接；第三电阻R3第二端分别与第一电容C1第二端、第二电容C2第一端以及比较器第二输入口连接；第二电容C2第二端接地；比较器与第一检测电路连接；第一检测电路与控制电路连接。

摘要： 本发明公开了灰飞虱致死基因片段Transcription factor IIB及其应用。本发明筛选出经干扰后能够导致灰飞虱死亡的序列如SEQ ID NO.1所示的灰飞虱致死基因片段Transcription factor IIB，利用该基因片段的dsRNA饲喂灰飞虱、褐飞虱，可有效地致死灰飞虱、褐飞虱，本发明对环境生态和食品都安全，为利用RNA干扰技术控制害虫提供了新途径。

摘要： 本发明公开了一种Factor II和Factor V基因多态性检测特异性引物和液相芯片，该液相芯片主要包括有：每种由5’端的tag序列和3’端针对目的基因突变位点的特异性引物序列组成的ASPE引物，所述特异性引物序列为：针对Factor II基因A140G位点的SEQ ID NO.7及SEQ ID NO.8；针对Factor II基因G78A位点的SEQ ID NO.9及SEQ ID NO.10；和/或针对FactorV基因G125A位点的SEQ ID NO.11及SEQ ID NO.12；有anti-tag序列包被的微球；扩增引物。本发明所提供的检测液相芯片的检测结果与测序法的吻合率高达100％，实现多个突变位点的野生型和突变型并行检测。

摘要： 本申请实施例公开了一种计算Q‑Factor的电路、方法、装置及电子设备，用于提高Q‑Factor的精确度。本申请实施例为：滤波电路、谐振网络、第一检测电路和控制电路；滤波电路包括第一电阻R1、第二电阻R2、第三电阻R3、第一电容C1、第二电容C2、放大器和比较器；谐振网络分别与控制电路和第一电阻R1第一端连接，第一电阻R1的第二端与放大器连接；放大器分别与第二电阻R2第一端和第三电阻R3第一端连接；第二电阻R2第二端分别与第一电容C1的第一端和比较器第一输入口连接；第三电阻R3第二端分别与第一电容C1第二端、第二电容C2第一端以及比较器第二输入口连接；第二电容C2第二端接地；比较器与第一检测电路连接；第一检测电路与控制电路连接。

摘要： 为了解决现有技术中测试工装测试误差大的问题，本公开提供了一种针对Pin‑Fin功率模块K‑factor的测试工装及方法，提高测试精度。包括液冷夹具本体和温控设备，温控设备连接有温度传感器，温度传感器包括螺纹部和检测部；液冷夹具本体处设有与温度传感器螺纹部配合的螺纹孔，用于液冷夹具本体与Pin‑Fin功率模块装配且温度传感器安装到螺纹孔后，温度传感器的检测部插入Pin‑Fin缝隙且紧挨Pin‑Fin功率模块的基板。本公开的技术方案中，测试工装可以检测基于稳态下的基板壳温，检测得到的基板壳温比现有技术中的温控设备内部油温更能反映Pin‑Fin功率模块芯片的温度，提高了芯片结温的测试精度，基于该基板壳温可以得出的K‑factor的精确度更高。

摘要： 本发明公开了灰飞虱致死基因片段Transcription factor IIB及其应用。本发明筛选出经干扰后能够导致灰飞虱死亡的序列如SEQ ID NO.1所示的灰飞虱致死基因片段Transcription factor IIB，利用该基因片段的dsRNA饲喂灰飞虱、褐飞虱，可有效地致死灰飞虱、褐飞虱，本发明对环境生态和食品都安全，为利用RNA干扰技术控制害虫提供了新途径。

摘要： 本发明公开了优化的Komagataella pastoris酵母α‑factor信号肽及应用。本发明对具有如SEQID NO:1所示氨基酸序列的Komagataella pastoris酵母α‑factor信号肽引入一个N糖基化位点，得到优化后的Komagataella pastoris酵母α‑factor信号肽，其氨基酸序列如SEQIDNO:3所示。本发明优化的α‑factor信号肽特别适用于引导外源蛋白在毕赤酵母中的分泌表达，与优化前信号肽相比，表达水平提高了25‑35倍，其应用有利于筛选到高表达菌株，具有降低生产成本、便于后续纯化等优势。

摘要： 本实用新型涉及变压器技术领域，具体涉及一种K‑FACTOR变压器的铁芯结构，包括第一芯柱、第二芯柱、第三芯柱、上铁轭以及下铁轭；所述铁芯结构还包括上夹板以及下夹板；所述上夹板通过第一螺丝将上夹板、第一卡块以及第一卡槽固定；所述下夹板通过第二螺丝将下夹板、第二卡块以及第二卡槽固定；所述下夹板设有固定座；所述上铁轭的顶部设有U形压件；所述固定座与U形压件之间设有对拉螺杆。本实用新型通过上下夹板和对拉螺杆共同作用实现了对芯柱水平方向和竖直方向上的夹持固定，并且上下夹板、对拉螺杆与芯柱之间都是通过螺丝锁接的，没有焊接过程，螺丝锁接易于实现自动化生产，生产效率高。

摘要： 本实用新型涉及变压器技术领域，具体涉及一种K‑FACTOR变压器，包括芯柱以及上铁轭、下铁轭；所述芯柱的表面设有次级线圈；所述次级线圈的表面设有初级线圈；所述静电屏蔽层包括第一屏蔽层、第二屏蔽层、第三屏蔽层以及第四屏蔽层；所述K‑FACTOR变压器还包括用于固定芯柱、上铁轭以及下铁轭的垂直固定机构；所述K‑FACTOR变压器还包括用于固定上铁轭以及下铁轭的水平固定机构。本实用新型通过设置第一屏蔽层、第二屏蔽层、第三屏蔽层以及第四屏蔽层，使用多层屏蔽结构，能够有效地减少谐波损耗对变压器的影响，另外，通过垂直固定机构以及水平固定机构能够使得芯柱、上铁轭以及下铁轭之间的连接更稳稳固，防止变压器震动。