American

摘要： This paper discusses the effective application of Language and Intercultural Critical Thinking Integrated Approach(LICTIA)in American literature class,which aims to enforce aesthetic experience and values education in literary teaching.Reading literary classics helps students cultivate cognitive/academic language proficiency,empathizing ability,critical thinking ability,and establish positive values system,thus facilitating the construction of a community of shared future for mankind.

摘要： Time:December 6-10,2019Venue:Baltimore Convention Center,Baltimore MD,USA Website:https://meeting.aesnet.org/American Epilepsy Society(AES)2019 Annual Meeting willtake place in Baltimore Convention Center,Baltimore MD,USA on December 6-10,2019.From best practices to breakthrough research,the AES 2019 Annual Meeting offers the most extensive education on everything epilepsy and an unparalleled opportunity to network with the brightest minds in the field.

摘要： Soil underneath a structure might affect the behavior and the overall response of the structure in seismic events. The role of loose soil conditions and the inclusion of soil-structure interaction (SSI) in the analysis are important issues that need to be addressed. Since steel structures are light, two configurations designed as spatial and perimeter are considered to study the effect of soil on the steel structural frames for the same building. The paper provides a parametric analysis on the influence of SSI on the overall performance of MRFs (Moment Resisting Frames) according to the provisions of Saudi Building Code (SBC) [1]. A case study has been developed in which spatial and perimeter moment resisting frames of 12, 6 and 3 stories residential buildings are designed using Saudi Building Code (SBC) prescriptions. A modal response spectrum analysis has been carried out to see the influence of SSI on the fundamental period of vibration, top story displacement and inter-story drift limitations. Moreover, a static non-linear analysis has been performed to investigate the performance of frames, thus allowing to identify the influence of SSI on the structural design of steel MRFs.

摘要： As an African American writer, Toni Morrison is good at portraying diversified characters in her books to show the real life of black people and their cultural identities. Morrison regards The Bluest Eye as a broken mirror in which black people's true life is presented.

摘要： BACKGROUND Type 1 diabetes(T1D)is a complex disease with a higher incidence in Europeans than other populations.The Colombians Living in Medellin(CLM)is admixed with ancestry contributions from Europeans,Native Americans(NAT)and Africans(AFR).AIM Our aim was to analyze the genetic admixture component at candidate T1D loci in Colombian individuals with the disease.METHODS Seventy-four ancestry informative markers(AIMs),which tagged 41 T1D candidate loci/genes,were tested by studying a cohort of 200 Northwest Colombia diseased individuals.T1D status was classified by testing for glutamic acid decarboxylase(GAD-65 kDa)and protein tyrosine-like antigen-2 autoantibodies in serum samples.Candidate loci/genes included HLA,INS,PTPN22,CTLA4,IL2RA,SUMO4,CLEC16A,IFIH1,EFR3B,IL7R,NRP1 and RNASEH1,amongst others.The 1,000 genome database was used to analyze data from 94 individuals corresponding to the reference CLM.As the data did not comply with a normal distribution,medians were compared between groups using the Mann-Whitney U-test.RESULTS Both T1D patients and individuals from CLM displayed mainly European ancestry(61.58 vs 62.06)followed by Native American(27.34 vs 27.46)and to a lesser extent the AFR ancestry(10.28 vs 10.65)components.However,compared to CLM,ancestry of T1D patients displayed a decrease of NAT ancestry at gene EFR3B(24.30 vs 37.10)and an increase at genes IFIH1(32.07 vs 14.99)and IL7R(52.18 vs 39.18).Also,for gene NRP1(36.67 vs 0.003),we observed a non-AFR contribution(attributed to NAT).Autoimmune patients(positive for any of two auto-antibodies)displayed lower NAT ancestry than idiopathic patients at the MHC region(20.36 vs 31.88).Also,late onset patients presented with greater AFR ancestry than early onset patients at gene IL7R(19.96 vs 6.17).An association analysis showed that,even after adjusting for admixture,an association exists for at least seven such AIMs,with the strongest findings on chromosomes 5 and 10(gene IL7R,P=5.56×10-6 and gene NRP1,P=8.70×10-19,respectively).CONCLUSION Although Colombian T1D patients have globally presented with higher European admixture,specific T1D loci have displayed varying levels of Native American and AFR ancestries in diseased individuals.

摘要： Time:December 6-10,2019Venue:Baltimore Convention Center,Baltimore MD,USA Website:https://meeting.aesnet.org/American Epilepsy Society(AES)2019 Annual Meeting will take place in Baltimore Convention Center,Baltimore MD,USA on December 6-10,2019.From best practices to breakthrough research,the AES 2019 Annual Meeting offers the most extensive education on everything epilepsy and an unparalleled opportunity to network with the brightest minds in the field.

摘要： 背景基层患者就诊时经常提出要做某些检查、治疗或者要求转诊。如何解决患者的这些请求,给临床医生带来了挑战。但是是否可以通过患者特征来预测其就诊请求,目前还鲜为人知。目的调查基层患者特征与其就诊时向医生提出请求之间的关系。研究设计、开展地点和研究对象本项横断面研究在一家教学家庭医生诊所开展。研究对象为1 141例成年患者,共接受了在此诊所工作的56例家庭医生(45例住院医生和11例教学医生)提供的1 319次诊疗服务。调查资料患者随访调查内容包括:就诊期间向医生提出做了哪些检查、处方和转诊情况、社会人口统计学特点、身心健康状况、受困扰或担忧的症状(自制3点量表评估,分数为3~15分;Cronbach’sα系数为0.83)、总体生活满意度、对诊疗服务的怀疑度、五因素人格特征。结果在867次(65.7%)的诊疗服务过程中,有患者向医生提出了诊疗要求。多因素分析表明,下列患者特征与其在就诊中提出要做某些检查、治疗或者转诊高度相关:年龄[IRR=1.01,95%CI(1.00,1.01)]、高度困扰或担忧的症状[IRR=1.06,95%CI(1.03,1.08)]、较为外向的性格[IRR=1.12,95%CI(1.03,1.08)]、较高的生活满意度[IRR=1.01,95%CI(1.00,1.02)]、同一位医生既往就诊史[IRR=1.17,95%CI(1.04,1.32)]。结论年长、高度担忧自己的症状或被症状高度困扰、外向、具有高度的总体生活满意度、具有同一位医生既往就诊史的患者在基层医疗机构就诊时会经常提出要做某些检查、治疗或者转诊要求。

摘要： In the summer of 2009, I attended an all-day environmental education workshop in Taipei. The event was conducted by two educators from northern Europe. One was from Germany and the other from Sweden. The audience was faculty and students from Taiwan Normal University.