摘要:
Through a variety of chromatographic techniques and spectroscopic methods,sixteen diterpenes were isolated and identified from the ethanol extraction of the roots of Salvia kiaometiensis Lévl.Their structures were identified to be 6,8,11,13-abietatetraen-12-ol dimer (1),kiaometin (2),miltirone (3),tanshinone ⅡA (4),crypotanshione (5),tanshindiol C (6),ferruginol (7),2-isopropyl-8-methylphenanthrene-3,4-dione (8),tanshinone Ⅰ (9),trijuganone B (10),dihydrotanshinone Ⅰ (11),grandifolias C (12),przewalskin (13),tanshinlactone (14),6,7,8,9-tetrahydro-1,6,6-trimethylfuro[3,2-c]naphtha[2,1-e]oxepine10,12-dione (15),and salmilalbanone (16).Compound 1 is a new abietane diterpenes dimer,and compound 2 is a new 7,8:7,20-diepoxy-nor-abietane diterpenes.All of the diterpenes were isolated from this plant for the first time.%对民间丹参代用品荞麦地丹参(Salvia kiaometiensis Lévl.)乙醇提取物进行化学成分研究,通过现代多种色谱技术和波谱技术,从中分离并鉴定16个二萜类化合物,分别是6,8,1 1,13-abietatetraen-12-ol dimer (1),kiaometin (2),miltirone(3),tanshinone ⅡA (4),crypotanshione (5),tanshindiol C (6),ferruginol (7),2-isopropyl-8-methylphenanthrene-3,4-dione(8),tanshinone Ⅰ (9),trijuganone B(10),dihydrotanshinone Ⅰ (11),grandifolias C(12),przewalskin (13),tanshinlactone (14),6,7,8,9-tetrahydro-1,6,6-trimethylfuro[3,2-c]naphtha[2,1-e]oxepine-10,12-dione (15),almilalbanone (16).其中,化合物1为新的松香烷型二萜的二聚体,2为新的降松香烷型二萜化合物,其B环7,8位开环后又通过醚桥连接起来.所有化合物均为首次从该种植物中得到.