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骨扫描

骨扫描的相关文献在1989年到2020年内共计99篇,主要集中在肿瘤学、临床医学、特种医学 等领域,其中期刊论文87篇、专利文献12篇;相关期刊68种,包括实用临床医药杂志、现代肿瘤医学、国际医学放射学杂志等; 骨扫描的相关文献由307位作者贡献,包括冯雪凤、许守林、何川等。

骨扫描—发文量

期刊论文>

论文:87 占比:87.88%

专利文献>

论文:12 占比:12.12%

总计:99篇

骨扫描—发文趋势图

骨扫描

-研究学者

  • 冯雪凤
  • 许守林
  • 何川
  • 冯建民
  • 刘志宏
  • 包丽华
  • 张炅
  • 王毅
  • 程旭
  • 胡旭东
  • 期刊论文
  • 专利文献

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    • 蔡建平; 樊员胜
    • 《中国医学装备》  | 2018年
    • 摘要: 目的:探讨核磁共振成像联合骨扫描在膝部骨肿瘤诊断中的临床应用价值.方法:选取医院明确诊断的70例膝部骨肿瘤患者,按照入院时影像学检查方式进行分组,行核磁共振成像(MRI)检查的患者纳入MRI检查组(37例),行骨扫描检查的患者纳入骨扫描检查组(14例),MRI联合骨扫描检查的患者纳入联合检查组(19例).收集3组患者的影像学检查图像及病理结果,分析影像学图像的病变性质、边界、范围、侵袭性及病变内部均匀性等指标;比较各检查技术在膝部骨肿瘤的诊断价值.结果:在膝部良性和恶性肿瘤的诊断符合率方面,联合检查组诊断符合率分别为100%和92.86%, MRI检查组分别为76.47%和70.0%,骨扫描检查组分别为57.14%和85.71%;MRI检查组与骨扫描组的诊断符合率比较,其差异无统计学意义(x2=2.336,P>0.05);MRI检查组与联合检查组良性和恶性的诊断符合率比较,其差异有统计学意义(x2=2.936,x2=3.524;P<0.05);骨扫描检查组与联合检查组的诊断符合率比较,其差异有统计学意义(x2=3.718, x2=2.947;P<0.05).3组对膝部肿瘤的边界、范围及内部均匀性等征象指标比较,其差异均有统计学意义(x2=4.001, x2=3.695,x2=2.852;P<0.05).结论:MRI联合骨扫描检查可部分提高膝部骨肿瘤的早期诊断效能,为临床提供更全面、可靠的影像资料,有利于改善患者的预后,具有较高的临床应用价值.%Objective: To investigate the clinical value of magnetic resonance imaging (MRI) combined with the diagnosis of bone scanning in bone tumors of knee. Methods: 70 patients with bone tumor of knee were enrolled in the research. And all of them were divided into MRI group (37 cases), bone scanning group (14 cases) and combined detection group (19 cases) according to different imageological examination mode when they were hospitalized. These images of imageological examination and pathological results were collected, and lesion property, lesion boundary, lesion range, invasiveness of lesion and homogeneousness of lesion interior in the images were analyzed and researched. The diagnostic values of various examination technique for bone tumor of knee were compared. Results:The diagnostic accordance rates of benign and malignant bone tumor of knee in the combined group were 100% and 92.86%, and they were 76.4% and 70% in MRI group, and they were 57.14% and 85.71% in bone scanning group. And the difference of diagnostic accordance rate between MRI group and bone scanning group was not significant (x2=2.336, P>0.05). The differences of diagnostic accordance rates of benign and malignant bone tumor of knee between MRI group and combined detection group were significant (x2=2.936, x2=3.524, P<0.05), respectively. And the diagnostic accordance rates of benign and malignant bone tumor of knee between bone scanning group and combined detection group also were significant (x2=3.718, x2=2.947, P<0.05), respectively. Besides, the differences of lesion boundary, lesion range and homogeneousness of lesion interior among the three group were significant (x2=4.001, x2=3.695, x2=2.852, P<0.05), respectively. Conclusion: The combination of MRI and bone scanning examination can partially increase the diagnostic efficiency at early stage for bone tumor of knee, and provide more comprehensive and more reliable image data for clinical practice. Therefore, it is beneficial to improve the prognosis of patients and it has higher application value in clinical practice.
    • 张炅; 刘志宏; 何川; 王毅; 冯建民
    • 《生物骨科材料与临床研究》  | 2018年
    • 摘要: 目的 研究髋关节置换术后正常的患者人群中99mTc三相同位素骨扫描结果,前瞻性的统计骨扫描对于人工髋关节置换术后无症状患者的诊断价值.方法 2015年4月至2015年12月随访全髋关节置换术后功能正常患者27例(男4;女23).单侧置换19例(右10;左9),双侧置换8例,共35个髋关节假体.所有患者进行Harris评估,患者均接受血清学检查和三相同位素骨扫描.结果 27例中4例(6髋)血沉超过正常值.4例(4髋)C-反应蛋白超过正常值.27例中25例三相同位素骨扫描为阴性,2例同位素骨扫描为阳性.血沉结果同临床症状之间阴性一致率82.86%;C-反应蛋白结果同临床症状之间阴性一致率88.57%;骨扫描结果同临床症状之间阴性一致率94.29%;三项联合运用结果同临床症状之间阴性一致率71.43%.结论 本组研究主要针对假体置换术后5年以上病例,假体稳定并且无症状.研究发现,27例(35髋)中25例(33髋)三相同位素骨扫描阴性.同位素骨扫描的阴性结果同临床症状的一致率94.29%,动态放射性核素显像能够反应骨与假体界面之间的血流变化,从而进一步判断假体周围感染.%Objective To investigate the 99mTc triple-phaseisotope bone scanning results fomormal patients after hip arthroplasty,prospectively analyze the diagnostic value ofisotope bone scan to asymptomatic patients after hip arthroplasty.Methods From Apr 2015 to Dec 2015,27 cases after total hip arthroplasty (4 males and 23 females) were followed up in outpatient department,in which 19 cases (10 fight side and 9 left side) were unilateral and 8 cases were bilateral.Harris hip joint function evaluation was taken in all cases.Both serological examinations and triple-phaseisotope bone scanning were performed in all cases.Results The erythrocyte sedimentation rate exceeded the normal range in 4 cases (6 hips) out of all the 27 cases,and the C-reactive protein value was higher than normal in 4 cases (4 hips).Of all the 27 cases,25 cases had negative results for the triple-phase bone scanning,while the rest 2 cases had positive results.The consistent negative rate between the results of erythrocyte sedimentation rate and clinical symptoms was 82.35%;consistent negative rate between the results of C-reactive protein and clinical symptoms was 88.24%;consistent negative rate between the results of bone scanning and clinical symptoms was 94.12%.When applying all these three diagnostic procedures federatively,consistent negative rate between the results of examinations and clinical symptoms was 71.43%.Conclusion This study mainly aimed at cases who had undergone prosthesis arthroplasty more than 5 years,with well prosthesis stability and no symptom.Results of this study have shown that,25 (33 hips) out of 27 cases (35 hips) had negative results for the triple-phase bone scanning.The concordance rate between the negative results of the isotope bone scan and clinical symptoms was 94.29%.Dynamic radionuclide imaging was able to reflect the blood flow changes on the interface between bone and the prosthesis,and go a step further to detect periprosthetic joint infection.
    • 卢洪辉; 耿建华; 罗小毛; 陈炜; 李占; 黄勇; 刘琳; 梁颖
    • 《中国医学装备》  | 2020年
    • 摘要: 目的:比较单光子发射计算机断层显像(SPECT)/CT不同扫描参数序列对骨断层图像质量和定量分析的影响,优化骨断层图像参数序列.方法:使用9组参数序列对jaszczak模体进行扫描,根据图像质量选出较好的3组参数序列,再用这3组参数序列进行NEMA IEC模体扫描和40例患者扫描,选出最好的1组参数序列,分别以每帧采集时间为5 s、10 s和15 s,每个采集时间步进角度分别为3°、4°和6°,两两组合共9组参数序列,即3°5 s、4°5 s、6°5 s、3°10 s、4°10 s、6°10 s、3°15 s、4°15 s和6°15 s,总共9组序列,对Jaszczak模体进行SPECT/CT断层扫描,对扫描图像进行本底变异系数(CV)测量和主观图像质量评级,从中选出图像质量较好的3组参数序列,进行美国国家电气制造商协会(NEMA)国际电工委员会(IEC)模体扫描和临床实验.采用NEMA IEC模体扫描比较3组参数序列的对比噪声比(CNR)及比放射性活度比值(RRA)差异.40例平面骨扫描显示放射性浓聚者行3组参数序列的骨断层扫描,比较3组采集参数序列的骨断层图像质量评级差别.结果:Jaszczak模体试验结果显示3°5 s、3°10 s和4°10 s的3组扫描参数序列CV分别为0.0636、0.0633和0.0735,图像质量评级分别为4等2级、4等3级和4等2级,可以兼顾图像质量和临床扫描时间.3°5 s、3°10 s和4°10 s的3个序列在直径≥13 mm的5个热灶测得的CNR均值分别为34.30、45.56和36.79;RRA均值分别为0.637、0.663和0.646.3组扫描参数序列的骨断层扫描主观图像评级结果显示3°5 s、3°10 s和4°10 s序列的平均值分别为3.675、3.975和4.075,三者差异有统计学意义(x2=16.137,P<0.05).其中3°10 s和4°10 s两组序列比较无统计学差异,但均高于3°5 s序列,差异有统计学意义(Z=-2.683,Z=-3.578;P<0.05).结论:3°10 s序列均可很好的兼顾总采集时长、图像质量和定量分析,适合作为断层骨显像的优选参数序列.
    • 温朔彬
    • 《温州人》  | 2020年
    • 摘要: 语言学家温端政是我的父亲。2020年年初,不幸在慢慢降临,我们却没有想到后果如此严重。父亲饭量逐渐减少,去当地山西省人民医院消化科看了几次,都因疫情的原因不接受住院,只开了一些帮助消化的药,然而不起作用。情况越来越严重,我们转院作了一个骨扫描,结果发现多处病变,不排除恶性肿瘤骨转移。主治医生办法用尽,仍然医治无效,最后不谈病情谈人生,劝父亲回家。
    • 白杲琛; 周利群; 宋毅; 张晓春; 赵峥; 谌诚; 虞巍; 韩文科; 何志嵩; 金杰
    • 《中华泌尿外科杂志》  | 2019年
    • 摘要: Objective To summarize the characteristics of clinical manifestation of bone flare after the treatment with new endocrine therapy in patients with metastatic castration-resistant prostate cancer (mCRPC) in order to evaluate the curative effect of patients properly and determine the reasonable treatment strategy.Methods We retrospectively analyzed the clinical data of two patients with mCRPC performed "bone flare" defined as PSA decline and bone metastases progression in the initial treatment with new endocrine therapy in Urology Department of Peking University First Hospital,and analyzed the clinical characteristics and treatment methods with the relative literature.Case 1,a 79-year-old man,presented with frequent urination and prostate-specific antigen (PSA) was 115.900 ng/ml,was diagnosed as prostate cancer (cT3N0M1) with bone metastasis.After androgen deprivation therapy of 24 months,PSA elevated and multiple bone metastases progressed.The patient was diagnosed with mCRPC and then began the treatment of enzalutamide.Case 2,a 62-year-old man,complained about emaciation and frequent urination,was diagnosed with prostate cancer(cT4N1M1)with bone and lymph metastases.After androgen deprivation therapy of 22 months,PSA elevated and multiple bone metastases progressed.The patient was diagnosed with mCRPC and then began the treatment of abiraterone.Results Case 1 was treated with enzalutamide and 2 months later PSA decreased from 133.400 ng/ml to 5.530 ng/ml,while bone scan showed multiple bone metastases,part of which was newly metastatic lesions.6 months later,the number of metastatic lesions kept stable,and part of lesions presented metabolism decrease.8 months later,the number of metastatic lesions began to decrease.1 year later,the patient started to receive chemical therapy because of the progression of the disease.After 5 cycles of chemotherapy,PSA progression occurred and chemotherapy was stopped.Liver failure and disseminated intravascular coagulation caused death in June 2016.Case 2 was treated with abiraterone and 2 months later PSA decreased from 54.820 ng/ml to 3.580 ng/ml,while bone scan showed multiple bone metastases,part of which was newly metastatic lesions.6 months later,the number of metastatic lesions began to decline.10 months later,the number of metastatic lesions kept stable.The treatment of abiraterone was continued so far and the patient was in a stable condition.Conclusions Enzalutamide and abiraterone,two new endocrine therapy,are determined as preferred methods for the treatment of mCRPC.The bone scanning is required to evaluate the possibility of "bone flare" which is defined as PSA decline and bone metastases progression in the initial treatment.These patients should be evaluated to make appropriate clinical decision.%目的 探讨新型内分泌治疗药物治疗转移性去势抵抗前列腺癌(mCPRC)患者出现“骨闪烁”的临床特点和处理方法.方法 回顾性分析2例服用新型内分泌治疗药物出现“骨闪烁”的mCRPC患者的临床病理资料,结合国内外文献,分析其临床特点和处理方法.病例1,79岁.2013年11月5日因尿频就诊.血PSA 115.900 ng/ml.MRI检查:前列腺右侧外周带T2相可见低信号区,累及包膜(考虑前列腺癌).骨扫描检查:多发骨转移.直肠指检:前列腺右侧叶质硬.行超声引导下经直肠前列腺穿刺活检术,病理诊断:前列腺腺癌,Gleason评分5±5=10分,局部可见肉瘤样分化,可见癌组织侵犯脉管、神经及脂肪组织.初始诊断:前列腺腺癌(cT3 N0M1).2013年11月开始雄激素剥夺治疗,PSA最低降至0.066 ng/ml.2015年1月PSA升至133.400 ng/ml,血清睾酮1.4nmol/L;影像学检查示全身多发骨转移进展.诊断为mCRPC,开始使用恩杂鲁胺治疗.病例2,62岁.2013年2月10日因消瘦伴尿频于外院就诊.PSA> 100 ng/ml.MRI检查:前列腺癌可能大,累及双侧精囊腺及邻近膀胱壁.胸部CT检查:纵隔、双肺门多发淋巴结转移.骨扫描检查:多发骨转移.直肠指检:前列腺明显增大,质硬.行超声引导下经直肠前列腺穿刺活检术,病理诊断:前列腺腺癌,Gleason评分4±4=8分,可见癌组织侵犯神经.初始诊断:前列腺腺癌(cT4N1 M1).2013年3月开始雄激素剥夺治疗,PSA最低降至0.517 ng/ml.2015年1月PSA升至43.180 ng/ml,血清睾酮0.9nmol/L;影像学检查示全身多发骨转移进展,诊断为mCRPC,开始使用阿比特龙治疗.结果 病例1使用恩杂鲁胺治疗2个月后PSA降至5.530 ng/ml,但骨扫描显示多发骨转移,部分为新发病灶,经骨科会诊无需骨科处理;治疗6个月时,转移灶数量稳定,部分病灶代谢降低;治疗8个月时,骨转移灶数量开始减少;治疗10个月时,骨转移灶开始重新增加.2016年1月,患者因病情进展停用恩杂鲁胺,开始接受全身化疗,化疗5个周期后出现PSA进展而停止化疗.2016年6月因弥散性血管内凝血、肝衰竭死亡.病例2使用阿比特龙治疗2个月后PSA从54.820 ng/ml降至3.580 ng/ml,骨扫描检查示多发骨转移,部分为新发病灶,经骨科会诊无需骨科处理;治疗6个月时,转移灶数量开始减少;10个月时,转移灶稳定.患者至今持续48个月阿比特龙治疗,病情稳定.结论 对于mCRPC患者,采用恩杂鲁胺及阿比特龙治疗早期可能会出现PSA下降、但骨扫描检查提示进展的“骨闪烁”现象,对其正确合理的评估才能让患者获得充分疗效.
    • 李云波; 何伟; 郭坤; 孙涛; 施乐; 袁梦晖; 魏龙晓
    • 《现代肿瘤医学》  | 2018年
    • 摘要: Objective:To compare the diagnostic performance of F - 2 - deoxyglucose(18 F - FDG)PET/ CT ima-ging and 99 Tcm - MDP bone scintigraphy in detecting bone metastasis. Methods:18 F - FDG PET/ CT and 99 Tcm -MDP bone scintigraphy were performed in 137 malignant tumor patients confirmed by pathology within one months. The sensitivity,specificity and accuracy were compared. Results:48. 2%(66 / 137)were positive in 99 Tcm - MDP bone scan,and in 71 patients with 99 Tcm - MDP negative 12 cases showed positive diagnosis with 18 F - FDG PET/ CT. 45. 3%(62 / 137)were positive in 18 F - FDG PET/ CT imaging,and in 75 patients with 18 F - FDG PET/ CT negative 16 cases showed positive diagnosis with 99 Tcm - MDP. There was no significance difference in detecting bone metasta-sis. The incidence in four types of bone change showed no significant statistical difference(P = 0. 173)and osteolytic metastasis vs osteoblastic showed significant statistical difference(P = 0. 018)according to CT features. Conclusion:There was no difference in detecting bone metastasis between 18 F - FDG PET/ CT and 99 Tcm - MDP scan. Howev-er,18 F - FDG PET/ CT was better for osteolytic and 99 Tcm - MDP was better for osteoblastic lesions.%目的:比较18 F-FDG PET/CT与99 Tcm-MDP骨显像对肿瘤骨转移灶的检出率,探讨两种方法在骨转移灶筛查中的价值.方法:137例确诊恶性肿瘤患者在1月内分别进行99 Tcm-MDP骨显像及18 F-FDG PET/CT显像,比较分析两者对骨转移灶检出率的结果.结果:137例患者之中66例患者99 Tcm-MDP骨显像为阳性,中轴骨、四肢骨均可出现,检出率为48.2%(66/137);71例骨显像阴性患者中有12例PET/CT结果为阳性.所有患者之中62例患者18F-FDG PET/CT为阳性,检出率为45.3%(62/137),75例PET/CT阴性患者中有16例骨扫描结果为阳性.两种方法检出率之间比较(P=0.068),差异无统计学意义;按四种骨质改变类型比较两种方法检出率(P=0.173),差异无统计学意义;按CT溶骨性与成骨性类型分类比较两种方法(P=0.018),两者差异有显著性意义.结论:18 F-FDG PET/CT与99 Tcm-MDP骨显像筛查恶性肿瘤骨转移灶效能无明显差别,18 F-FDG PET/CT优势在于发现溶骨性病变,而99 Tcm-MDP骨显像的优势为成骨性改变.
    • 费剑锋; 阳青松; 陆建平
    • 《放射学实践》  | 2019年
    • 摘要: 前列腺癌是男性常见的恶性肿瘤,晚期前列腺癌易发生骨转移及淋巴结转移,检测评估前列腺癌转移病灶对治疗方式的选择、远期预后判断有重要意义.当前,传统影像学检查已经难以满足临床需求,很多新的影像检查手段已经逐渐应用于临床.本综述主要对当前临床常用的检查方法进行归纳总结,从机制、优缺点及检测效能等方面进行阐述,从而更好地指导临床治疗及评估患者预后.
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