摘要:
A total of 820 patients who visited Endocrinology department in our hospital were enrolled in the study from June 2016 to May 2018. These patients were divided into diabetic retinopathy ( DR ) and non-diabetic retinopathy ( NDR) groups according to the occurrence of DR. Factors such as gender, age, course of diabetes, smoking/drinking history, family history of diabetes, and onset age of diabetes were compared between the two groups, and logistic regression was used to analyze the risk factors of DR. The results showed that there were 387 smoker( 47. 2%) and 433 non-smoker ( 52. 8%) in 820 tyge 2 diabetic patients, and 339 ( 41. 3%) patients were diagnosed with DR. There were no statistical differences in gender, age, body mass index, family history of diabetes, drinking history, and HbA1C between the two groups. Logistic regression analysis showed that duration of diabetes (OR=2.653,P<0.001), hypertension(OR=1.371,P=0.041),onset age of diabetes<40years(OR=1.526,P=0.028) , and adolescent smoking history( OR=2.178,P<0.001) were independent risk factors for DR.%入选2016年6月至2018年5月来本院内分泌科就诊的820例2型糖尿病患者,根据糖尿病视网膜病变(DR)发生情况分为DR组及非DR组,比较2组之间性别、年龄、糖尿病病程、吸烟情况、饮酒、糖尿病家族史、糖尿病发病年龄等指标.应用logistic回归分析探讨DR的危险因素.结果显示,入组患者有吸烟史患者387例(47.2%),不吸烟者433例(52.8%),合并有DR患者339例(41.3%),青少年期间有吸烟史患者129例,68例(52.7%)合并有DR.DR与非DR组患者在性别、年龄、体重指数、糖尿病家族史、饮酒史、HbA1C方面差异无统计学意义.Logistic回归分析发现高血压(OR=1.371,P=0.041)、糖尿病发病年龄<40岁(OR=1.526,P=0.028)、糖尿病病程(OR=2.653,P<0.001)及青少年吸烟史(OR=2.178,P<0.001)是DR发生的独立危险因素.