摘要:
目的:研究分析通便汤治疗小儿功能性便秘食积证的安全性及疗效.方法:选取符合纳入标准的96例功能性便秘食积证患儿作为研究对象,将其随机分为两组,治疗组48例患儿采用通便汤进行治疗,对照组48例患儿采用思连康片和乳果糖进行治疗.对比两组患儿的治疗效果、不良反应情况、治疗结束后的排便时间和排便间隔时间.结果:治疗1周时,治疗组患儿的治疗总有效率为81.25%,对照组为75.00%;治疗2周时,治疗组患儿的治疗总有效率为85.42%,对照组为77.08%;治疗3周时,治疗组患儿的治疗总有效率为91.67%,对照组为77.08% (P <0.05).治疗结束后2周时,治疗组患儿的治疗总有效率为97.92%,对照组为79.17% (P <0.01).治疗组患儿中有2例(4.17%)发生了不良反应,对照组中有9例(18.75%)发生不良反应,两组比较具有显著性差异(P<0.05).治疗结束1个月时,治疗组患儿排便时间低于15 min的比例为87.50%,明显高于对照组的68.75% (P <0.05);治疗组患儿的排便间隔时间低于3天的比例为95.83%,明显高于对照组的79.17% (P <0.05).结论:对于功能性便秘食积证患儿,采用通便汤进行治疗的疗效好、安全性高,不良反应率低、排便时间短、排便间隔时间短.%Objective:To study the safety and efficacy of Laxative decoction on children with functional constipation and indigestion syndrome.Methods:96 children with functional constipation and indigestion syndrome who met the criteria were randomly divided into two groups.48 children in group A were treated with Laxative decoction;48 children in group B were treated with Bifidobacterium Tetravaccine tablets and lactulose.The efficacy adverse reaction,defecation time and defecation interval between two groups were recorded and compared.Results:After a week of treatment,the total effective rate in group A was 81.25 % and was higher than that of 75.00% in group B;after treatment of two weeks,the total effective rate in group A was 85.42% and was higher than that of 77.08% in group B;after treatment of three weeks,the total effective rate in group A was 91.67% and was higher than that of 77.08% in group B(P <0.05);two weeks after the completion of treatment,the total effective rate in group A was 97.92% and was higher than that of 79.17% in group B (P <0.01);in group A two cases (4.17%) had adverse reactions,while in group B there were nine cases (18.75%)with adverse reactions (P <0.05);the proportion of the defecation time that was shorter than 15 min in group A was 87.50%,which was significantly higher than that of 68.75% in group B (P < 0.05);the proportion of defecation interval time that was shorter than 3 days in group A was 95.83%,which was significantly higher than that of 79.17% in group B (P < 0.05).Conclusion:For the children with functional constipation and indigestion syndrome,the therapeutic effect of Laxative decoction is good,with high safety,low adverse reaction rate,short defecation time and defecation interval time.