9.0

摘要： 高校为谁培养人、如何培养人、培养什么样的人一直是我们探讨的重要话题,当前,在校大学生主要是由"00后"构成,而高校辅导员这支队伍逐渐开始年轻化,大都由"90后"组成,现阶段,心理健康问题已经成为影响大学生是否顺利毕业、健康成长的重要因素.因此,在此背景下,作为"90后"辅导员,如何做到减少代际障碍,做好"00后"大一新生的心理健康教育至关重要.

摘要： 为了丰富广温性潮间带底栖生物的温度调控机制研究,本研究采用荧光定量PCR法、亚硫酸氢盐处理基因组DNA结合甲基化特异性PCR(Methylation specific PCR,MSP)法及染色质免疫共沉淀法,对40°C热胁迫24 h后,近江牡蛎(Crassostrea rivularis)热休克蛋白90(Heat shock protein 90,Hsp90)的mRNA表达及其核心启动子甲基化的调控模式进行研究.结果显示:近江牡蛎成贝在40°C热胁迫24 h后,其消化腺、腮和心脏组织中Hsp90 mRNA表达显著升高(P0.05),灰度分析显示消化腺和心脏组织中的Hsp90核心启动子与RNA聚合酶Ⅱ(RNA polymeraseⅡ)结合增强,腮组织中的Hsp90核心启动子与RNA polymeraseⅡ出现弱结合.表明Hsp 90是近江牡蛎抵御高温胁迫的主要表达基因.

摘要： 曾几何时,一群被贴着叛逆、跋扈、非主流标签的少年,已长成如今独立、创新、有自己主张的青年模样,这群人叫做九零后。积厚流光,有所老院沐着摇曳战火而生,一代又一代的人在这院儿里年轻又老去,将一次又一次的活力碰撞成文化,谱写成底蕴,这所老院是大连大学附属中山医院。

摘要： BACKGROUND Primary appendiceal cancers are rare,and they generally present with liver and/or peritoneal metastases.Currently there are no guidelines to treat metastatic appendiceal cancer,and hence they are treated as metastatic colorectal cancer.Combining Yttrium 90(Y-90)radioembolization(RE)with systemic chemotherapy early in the treatment of right sided colon cancers has been shown to improve survival.Based on this data,a combination of systemic chemotherapy and Y-90 RE was used to treat a case of metastatic appendiceal cancer.CASE SUMMARY A 76-year-old male presented to the emergency room with progressive right lower quadrant pain.A Computed Tomography of the abdomen and pelvis was performed which showed acute appendicitis and contained perforation.Urgent laparoscopic appendectomy was then followed by histological analysis,which was significant for appendiceal adenocarcinoma.After complete workup he underwent right hemicolectomy and lymph node dissection.He received adjuvant chemotherapy as the local lymph nodes were positive.Follow-up imaging was significant for liver metastasis.Due to rapid growth of the liver lesions and new peritoneal nodules,the patient was treated with a combination of Y-90 RE and folinic acid,fluorouracil,and irinotecan with bevacizumab and not microwave ablation as previously planned.Follow up imaging demonstrated complete response of the liver lesions.At 12-mo follow-up,the patient continued to enjoy good quality of life with no recurrent disease.CONCLUSION Utilization of Y-90 RE concomitantly with systemic chemotherapy early in the treatment of appendiceal cancer may provide improved control of this otherwise aggressive cancer.

摘要： BACKGROUND The hepatic arterial anatomy is highly variable, with the two most common variants being a replaced right hepatic artery(RHA) originating from the superior mesenteric artery(SMA) and a left hepatic artery(LHA) originating from the left gastric artery(LGA). These anatomical variants could potentially increase the risk for non-target embolization during Y90-Radioembolization due to the close proximity between hepatic and enteric vessel branches.AIM To evaluate the safety of Yttrium-90radioembolization(90Y-RE) with resin microspheres in patients with a variant hepatic arterial anatomy.METHODS In this retrospective single-center observational study, 11 patients who underwent RE with 90Y-resin microspheres via a LHA originating from the LGA,and 13 patients via a RHA originating from the SMA were included. Patient and treatment data were reviewed regarding clinical and imaging evidence of nontarget embolization of 90Y-resin microspheres to the GI tract. Positioning of the tip of the microcatheter in relationship to the last hepatoenteric side branch was retrospectively analyzed using angiographic images, cone-beam CT and preinterventional CT-angiograms.RESULTS None of the 24 patients developed clinical symptoms indicating a potential nontarget embolization to the GI tract within the first month after 90Y-RE. On thepostinterventional 90Y-bremsstrahlung images and/or 90Y-positron emission tomographies, no evidence of extrahepatic 90Y-activity in the GI tract was noted in any of the patients. The mean distance between the tip of the microcatheter and the last enteric side branch during delivery of the 90Y microspheres was 3.2 cm(range: 1.9-5 cm) in patients with an aberrant LHA originating from a LGA. This was substantially shorter than the mean distance of 5.2 cm(range: 2.9-7.7 cm) in patients with an aberrant right hepatic originating from the SMA.CONCLUSION90Y-RE via aberrant hepatic arteries appears to be safe;at least with positioning of the microcatheter tip no less than 1.9 cm distal to the last hepatoenteric side branch vessel.

摘要： 中职生是国家高素质劳动人才资源的重要后备力量,其身心健康直接关系到自身和未来社会的良好发展.体育课程不仅对学生的身体素质的提高发挥着重要的作用,而且对学生的心理健康教育也有着其它学科不能替代的优势.所以通过体育课程的合理按排,对学生心理健康的有效干预和心理素质的培养,有着非常重要的意义.

摘要： 良好的职业形象对高校思想政治工作者以及辅导员个人都具有积极的促进作用，长春市“90 后”辅导员的职业形象整体向好，且自我要求高于他者要求，但“思想政治工作者”这一根本身份不突出。这一现象的产生离不开长春市高校合理的选拔培养机制，“90 后”辅导员主体强烈的自尊意识以及过分沉溺事务性工作等原因。