摘要：
目的:研究无抽搐电休克治疗(M ECT)对精神分裂症患者短时记忆及恢复周期的影响.方法:40例接受M ECT治疗的精神分裂症患者,分别于治疗前、治疗后、治疗后4周采用阳性与阴性症状量表(PANSS)评估精神症状,分别于治疗前、治疗后、治疗后1周、治疗后2周、治疗后4周采用修订韦氏记忆量表(WM S)测定记忆商数(M Q)和定向、记图等各维度得分评价记忆水平.结果:治疗后和治疗后4周PANSS评分均低于治疗前,且治疗后4周低于治疗后,差异有统计学意义(P<0.05).M ECT治疗后M Q总分为低于治疗前,治疗后1周、2周、4周均高于治疗后,差异均有统计学意义(P<0.05).各维度中,治疗后记图评分显著低于治疗前,治疗后4周定向、累加、再认、联想、理解评分显著高于治疗前,差异有统计学意义(P<0.05).结论:M ECT 治疗可显著改善精神分裂症患者精神症状,但会引起短时记忆损伤,治疗后1周可逐渐恢复到治疗前水平,且部分维度的记忆能力较治疗前改善.%Objective:To study the Modified Electroconvulsive Therapy on short-term memory damage and recovery cycle of schizophrenic patients.Methods:The mental symptoms of 40 schizophrenia patients with MECT treatment before and after treatment,4 weeks after treatment were evaluated by positive and negative symptoms scale(PANSS),The memory before and 2 weeks after treatment,4 weeks after treatment were evaluated by memo-ry quotient(MQ)and orientation,remember each dimension score revised by wechsler memory scale(WMS).Re-sults:The PANSS score 4 weeks after treatment and after treatment were lower than before treatment,and 4 weeks after treatment was lower than after treatment,the difference was statistically significant(P<0.05).After treat-ment of MECT,the total MQ score was lower than before treatment,and the difference was statistically significant (P<0.05),1 week,2 weeks and 4 weeks after treatment were higher than after treatment for the difference was sta-tistically significant(P<0.05).Among all dimensions,postscript figure score after treatment was significantly lower than before treatment,the directional,accumulate,recognition,lenovo,understanding score 4 weeks after treatment were significantly higher than before the treatment,the difference was statistically significant(P<0.05).Conclu-sion:MECT treatment can significantly improve mental symptoms in patients with schizophrenia,but can cause short-term memory damage,1 week after treatment it can be gradually restored to the level before treatment,and memory ability is improved.
